Evidence map›Paper›PMID 37273629›Full record

ArticleACS omega2023

PS9, Derived from an Aquatic Fungus Virulent Protein, Glycosyl Hydrolase, Arrests MCF-7 Proliferation by Regulating Intracellular Reactive Oxygen Species and Apoptotic Pathways.

Manikandan Velayutham, Purabi Sarkar, Kanchana M Karuppiah, Priyadharsan Arumugam, Shanavas Shajahan, Mohammad Abu Haija, Tansir Ahamad, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Ki-Choon Choi and 2 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Manikandan VelayuthamDepartment of Medical Biotechnology and Integrative Physiology, Institute of Biotechnology, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai 602105, Tamil Nadu, India.
Purabi SarkarDepartment of Molecular Medicine, School of Allied Healthcare and Sciences, Jain Deemed-to-be University, Whitefield, Bangalore 560066, Karnataka, India.
Kanchana M KaruppiahDepartment of Medical Research, Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, Tamil Nadu, India.
Priyadharsan ArumugamDepartment of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, SIMATS, Chennai 600077, Tamil Nadu, India.
Shanavas ShajahanDepartment of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, SIMATS, Chennai 600077, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-9711-7165
Mohammad Abu HaijaDepartment of Chemistry, Khalifa University of Science and Technology, P.O. Box 127788, Abu Dhabi, United Arab Emirates.ORCID https://orcid.org/0000-0002-5846-0662
Tansir AhamadDepartment of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Mariadhas Valan ArasuDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Naif Abdullah Al-DhabiDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Ki-Choon ChoiGrassland and Forage Division, National Institute of Animal Science, RDA, Seonghwan-Eup, Cheonan-Si, Chungnam 330-801, Republic of Korea.
Ajay GuruDepartment of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, SIMATS, Chennai 600077, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-8583-9352
Jesu ArockiarajDepartment of Biotechnology, College of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, Tamil Nadu, India.
King Saud University · SASaveetha University · INKhalifa University of Science and Technology · AESRM Institute of Science and Technology · INJain University · INNational Institute of Animal Science · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most common diseases in women is breast cancer, which has the highest death globally. Surgery, chemotherapy, hormone treatments, and radiation are the current treatment options for breast cancer. However, these options have several adverse side effects. Recently, peptide-based drugs have gained attention as anticancer therapy. Studies report that peptides from biological toxins such as venom and virulent pathogenic molecules have potential therapeutic effects against multiple diseases, including cancers. This study reports on the

Identifiers

PMID37273629
PMCPMC10233697
OpenAlexW4377043077

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.