Evidence map›Paper›PMID 37273621›Full record

ArticleACS omega2023

New Natural Eugenol Derivatives as Antiproliferative Agents: Synthesis, Biological Evaluation, and Computational Studies.

Syed Nazreen, Serag Eldin I Elbehairi, Azizah M Malebari, Nuha Alghamdi, Reem F Alshehri, Ali A Shati, Nada M Ali, Mohammad Y Alfaifi, Ahmed A Elhenawy, Mohammad Mahboob Alam

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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  3. Future medicinal chemistry · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Syed NazreenDepartment of Chemistry, Faculty of Science, Al-Baha University, Al-Baha 65799, Kingdom of Saudi Arabia.
Serag Eldin I ElbehairiDepartment of Biology, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.
Azizah M MalebariDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Kingdom of Saudi Arabia.
Nuha AlghamdiDepartment of Chemistry, Faculty of Science, Al-Baha University, Al-Baha 65799, Kingdom of Saudi Arabia.
Reem F AlshehriChemistry Department, Faculty of Science and Art, Taibah University, Al Ula, Madinah 16857, Kingdom of Saudi Arabia.
Ali A ShatiDepartment of Biology, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.
Nada M AliDepartment of Chemistry, Faculty of Science, Al-Baha University, Al-Baha 65799, Kingdom of Saudi Arabia.
Mohammad Y AlfaifiDepartment of Biology, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.
Ahmed A ElhenawyChemistry Department, Faculty of Science, Al-Azhar Unuversity, 11884 Nasr City, Cairo 11751, Egypt.ORCID https://orcid.org/0000-0003-2893-0376
Mohammad Mahboob AlamDepartment of Chemistry, Faculty of Science, Al-Baha University, Al-Baha 65799, Kingdom of Saudi Arabia.
Al Baha University · SAKing Khalid University · SAAl-Azhar University · EGKing Abdulaziz University · SATaibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Semisynthetic modifications of natural products have bestowed us with many anticancer drugs. In the present work, a natural product, eugenol, has been modified synthetically to generate new anticancer agents. The final compounds were structurally confirmed by NMR, IR, and mass techniques. From the cytotoxicity results, compound

Identifiers

PMID37273621
PMCPMC10233844
OpenAlexW4376610601

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.