ArticleStructural heart : the journal of the Heart Team2022
Cardiac Damage Staging Classification in Asymptomatic Moderate or Severe Primary Mitral Regurgitation.
Article in Structural heart : the journal of the Heart Team, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Cardiac Damage Staging in Moderate or Greater Aortic Regurgitation: A New Framework for Risk Stratification.Structural heart : the journal of the Heart Team · 2026Article
- Increasing Left Ventricular Mass and Death in Men and Women Investigated With Echocardiography.Journal of the American Heart Association · 2025Article
- Transcatheter mitral valve replacement or repair for mitral regurgitation: a narrative review.Indian journal of thoracic and cardiovascular surgery · 2025Review
- Prognostic Implications of Cardiac Magnetic Resonance Imaging Characteristics in Primary Mitral Regurgitation.JACC. Advances · 2025Article
- The Staging of Cardiac Damage for Aortic Stenosis: A Review.Structural heart : the journal of the Heart Team · 2025Review
- Article
- Cardiac Damage Staging Predicts Outcomes in Aortic Valve Stenosis After Aortic Valve Replacement: Meta-Analysis.JACC. Advances · 2024Article
- Quantification of primary mitral regurgitation by echocardiography: A practical appraisal.Frontiers in cardiovascular medicine · 2023Review
Corrections and comments
- Erratum issued
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Optimal timing for intervention remains uncertain in asymptomatic patients with primary mitral regurgitation (MR). We aimed to assess the prognostic value of a new cardiac damage staging classification in patients with asymptomatic moderate or severe primary MR. Methods: Clinical, Doppler-echocardiographic, and outcome data prospectively collected in 338 asymptomatic patients (64 ± 15 years, 68% men) with at least moderate primary MR were retrospectively analyzed. Patients were hierarchically classified as per the following staging classification: no cardiac damage (stage 0), mild left ventricular or left atrial damage (stage 1), moderate or severe left ventricular or left atrial damage (stage 2), pulmonary vasculature or tricuspid valve damage (stage 3), or right ventricular damage (stage 4). Results: There was a stepwise increase in 10-year mortality rates as per cardiac damage stage: 20.0% in stage 0, 25.6% in stage 1, 31.5% in stage 2, and 61.3% in stage 3-4 ( Conclusions: The new staging classification provides independent and incremental prognostic value in patients with asymptomatic moderate or severe MR.
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