Evidence map›Paper›PMID 37273445›Full record

ReviewNational journal of maxillofacial surgery

Platelet-rich plasma protein as a therapeutic regimen for oral lichen planus: An evidence-based systematic review.

Nisha Maddheshiya, Adit Srivastava, Varun Rastogi, Amlendu Shekhar, Neha Sah, Ajay Kumar

Open access · hybridAbstract readReview
In one paragraph

Review in National journal of maxillofacial surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. [Treatment of oral lichen planus-a review].Dermatologie (Heidelberg, Germany) · 2025
    Review
  4. PRF and PRP in Dentistry: An Umbrella Review.Journal of clinical medicine · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Nisha MaddheshiyaDepartment of Oral Medicine and Radiology, Faculty of Dental Sciences, I.M.S, B.H.U, Azamgarh, Uttar Pradesh, India.
Adit SrivastavaDepartment of Oral Medicine and Radiology, Faculty of Dental Sciences, I.M.S, B.H.U, Azamgarh, Uttar Pradesh, India.
Varun RastogiDepartment of Oral and Maxillofacial Pathology, University College of Medical Sciences, Bhairawa, Nepal.
Amlendu ShekharDepartment of Oral Medicine and Radiology, Faculty of Dental Sciences, I.M.S, B.H.U, Azamgarh, Uttar Pradesh, India.
Neha SahDepartment of Oral and Maxillofacial Surgery, Dental College, Azamgarh, Uttar Pradesh, India.
Ajay KumarDepartment of Oral Medicine and Radiology, Faculty of Dental Sciences, I.M.S, B.H.U, Azamgarh, Uttar Pradesh, India.
College of Medical Sciences · NPCreative Commons · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral Lichen Planus (OLP), an autoimmune disorder of unclear pathogenesis affects quality of life of affected individual. Intervention regimens are multiple and still evolving due to its resistance to recover and ability to recur. Platelet rich Plasma (PRP) is a newer, promising treatment modality tested by researchers because of its low cost and negligible adverse effects. Articles were retrieved from search engines of PubMed / Medline, Scopus and Web of Science which fulfilled the eligibility criteria. Cochrane risk of bias tool assessed quality of clinical studies and Joanna Briggs Institute for case reports. A total of 4 articles were included for the systematic review, of which 2 are clinical trials and 2 case reports. All cases were of erosive nature. PRP in case reports were administered when patients did not respond to conventional therapy. PRP demonstrated effective therapeutic benefit in regards to outcome of pain and lesion appearance. PRP can be considered as a potential alternative therapy in treating non-responsive OLP. Further studies are recommended to arrive at a definitive conclusion.

Indexed as

Erythemamucocutaneousoral lichen planuspainplatelet-rich plasma

Identifiers

PMID37273445
PMCPMC10235744
OpenAlexW4366319735

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.