Evidence map›Paper›PMID 37273201›Full record

ArticlemSphere2023

Therapeutic potential of

Md Huzzatul Mursalin, Roger Astley, Phillip S Coburn, Eddy Bagaruka, Jonathan J Hunt, Vincent A Fischetti, Michelle C Callegan

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Infection and immunity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Md Huzzatul MursalinDepartment of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Roger AstleyDean McGee Eye Institute, Oklahoma City, Oklahoma, USA.
Phillip S CoburnDepartment of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.ORCID 0000-0003-3799-5251
Eddy BagarukaOklahoma Christian University, Edmond, Oklahoma, USA.
Jonathan J HuntOklahoma Christian University, Edmond, Oklahoma, USA.
Vincent A FischettiLaboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, New York, USA.
Michelle C CalleganDepartment of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.ORCID 0000-0002-1400-8586
Dean McGee Eye Institute · USOklahoma Christian University · USRockefeller University · USUniversity of Oklahoma Health Sciences Center · US

Funding

P30-CENTER CORE GRANT FOR VISION RESEARCHP30EY021725 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Michelle C Callegan, MICHAEL H ELLIOTT · 2011 to 2026
$10.5M
Staphylococcus Biology in Ocular InfectionsR01EY032073 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI CALLEGAN, MICHELLE C · 2021 to 2025
$1.8M
Pathogenic Mechanisms of Bacillus EndophthalmitisR01EY028810 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI CALLEGAN, MICHELLE C · 2018 to 2022
$1.8M
Semantic Guidance of Visual AttentionR01EY021802 · NEI · UNIVERSITY OF MASSACHUSETTS BOSTON · PI POMPLUN, MARC · 2012 to 2014
$653k
Targeting Chemokines in Intraocular InfectionR21EY028066 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI CALLEGAN, MICHELLE C · 2019 to 2020
$399k
Phage-Based Therapeutics for Ocular InfectionsR21EY031802 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI CALLEGAN, MICHELLE C · 2020 to 2021
$392k
NEI NIH HHS P30 EY021725NEI NIH HHS R01 EY021802NEI NIH HHS R01 EY028810NEI NIH HHS R01 EY032073NEI NIH HHS R21 EY028066NEI NIH HHS R21 EY031802
6 · The paper itself

Abstract

Bacteriophage lytic enzymes (i.e., phage lysins) are a trending alternative for general antibiotics to combat growing antimicrobial resistance. Gram-positive

Indexed as

BacillusBacillus PhagesEndophthalmitisEye Infections, BacterialAnimalsAnti-Bacterial AgentsHumansRabbitsAnti-Bacterial AgentsBacillusbacteriophage lysinendophthalmitiskeratitisocular infection

Identifiers

PMID37273201
PMCPMC10449515
OpenAlexW4379375728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.