Evidence map›Paper›PMID 37273197›Full record

ReviewExpert review of neurotherapeutics

Recent advances in treatment of spatial neglect: networks and neuropsychology.

Alex R Carter, A M Barrett

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of neurotherapeutics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Alex R CarterDepartment of Neurology, Department of Orthopedic Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
A M BarrettDepartment of Neurology, UMass Chan Medical School and UMass Memorial Healthcare, Worcester, MA, USA.
UMass Memorial Health Care · USWashington University in St. Louis · US

Funding

Optimizing Hand Rehabilitation Post-Stroke Using Interactive Virtual EnvironmentsR01HD058301 · NICHD · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI ADAMOVICH, SERGEI V, MERIANS, ALMA S · 2009 to 2021
$4.7M
Building a science for treatment of spatial neglectR01NS055808 · NINDS · KESSLER FOUNDATION, INC. · PI BARRETT, A. M. · 2008 to 2011
$1.6M
Spatial neglect and bias in near and far spaceK02NS047099 · NINDS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BARRETT, A. M. · 2004 to 2008
$746k
Mentoring translational cognitive science for stroke recoveryK24HD062647 · NICHD · KESSLER FOUNDATION, INC. · PI BARRETT, A. M. · 2010 to 2014
$695k
Prism adaptation treatment (PAT) for right brain stroke rehabilitationI01RX003662 · VA · NORTHAMPTON VA MEDICAL CENTER · PI A. M. Barrett · 2023 to 2026
–
A biomarker for personalized care in post-stroke spatial neglectI21RX003760 · VA · VETERANS HEALTH ADMINISTRATION · PI BARRETT, A. M. · 2021 to 2024
–
NICHD NIH HHS K24 HD062647NICHD NIH HHS R01 HD058301NINDS NIH HHS K02 NS047099NINDS NIH HHS R01 NS055808RRD VA I01 RX003662RRD VA I21 RX003760
6 · The paper itself

Abstract

introductionSpatial neglect remains an underdiagnosed and undertreated consequence of stroke that imposes significant disability. A growing appreciation of brain networks involved in spatial cognition is helping us to develop a mechanistic understanding of different therapies under development. AREAS COVERED: This review focuses on neuromodulation of brain networks for the treatment of spatial neglect after stroke, using evidence-based approaches including 1) Cognitive strategies that are more likely to impact frontal lobe executive function networks; 2) Visuomotor adaptation, which may depend on the integrity of parietal and parieto- and subcortical-frontal connections and the presence of a particular subtype of neglect labeled Aiming neglect; 3) Non-invasive brain stimulation that may modulate relative levels of activity of the two hemispheres and depend on corpus callosum connectivity; and 4) Pharmacological modulation that may exert its effect primarily via right-lateralized networks more closely involved in arousal. EXPERT OPINION: Despite promising results from individual studies, significant methodological heterogeneity between trials weakened conclusions drawn from meta-analyses. Improved classification of spatial neglect subtypes will benefit research and clinical care. Understanding the brain network mechanisms of different treatments and different types of spatial neglect will make possible a precision medicine treatment approach.

Indexed as

Perceptual DisordersStrokeBrainFrontal LobeHumansNeuropsychologySpace PerceptionAiming neglectbrain networksneuromodulationprecision medicineprism adaptationrehabilitationspatial neglectstroketranscranial magnetic stimulationvisual scanning

Identifiers

PMID37273197
PMCPMC10740348
OpenAlexW4379376861

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.