Evidence map›Paper›PMID 37272774›Full record

ArticleHead & neck2023

Outcomes after definitive treatment for cutaneous angiosarcomas of the face and scalp: Reevaluating the role of surgery and radiation therapy.

Alison K Yoder, Ahsan S Farooqi, Cort Wernz, Aparna Subramaniam, Vinod Ravi, Ryan Goepfert, Erich M Sturgis, Devarati Mitra, Andrew J Bishop, B Ashleigh Guadagnolo

Open access · greenAbstract read
In one paragraph

Article in Head & neck, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alison K YoderDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-2606-3814
Ahsan S FarooqiDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, Texas, USA.
Cort WernzBaylor College of Medicine, Houston, Texas, USA.
Aparna SubramaniamDepartment of Sarcoma Medical Oncology, MD Anderson Cancer Center, Houston, Texas, USA.
Vinod RaviDepartment of Sarcoma Medical Oncology, MD Anderson Cancer Center, Houston, Texas, USA.
Ryan GoepfertDepartment of Head and Neck Surgery, MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-3291-841X
Erich M SturgisDepartment of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.
Devarati MitraDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, Texas, USA.
Andrew J BishopDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, Texas, USA.
B Ashleigh GuadagnoloDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, Texas, USA.
The University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Institutional Career Development CoreKL2TR003168 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILLER, CHARLES C · 2019 to 2023
$4.9M
NCATS NIH HHS KL2 TR003168NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

introductionWe investigated outcomes and prognostic factors for patients treated for cutaneous angiosarcoma (CA).

methodsWe conducted a retrospective review of patients treated for CA of the face and scalp from 1962 to 2019. All received definitive treatment with surgery, radiation (RT), or a combination (S-XRT). The Kaplan-Meier method was used to estimate outcomes. Multivariable analyses were conducted using the Cox proportional hazards model.

resultsFor the 143 patients evaluated median follow-up was 33 months. Five-year LC was 51% and worse in patients with tumors >5 cm, multifocal tumors, those treated pre-2000, and with single modality therapy (SMT). These remained associated with worse LC on multivariable analysis. The 5-year disease-specific survival (DSS) for the cohort was 56%. Tumor size >5 cm, non-scalp primary site, treatment pre-2000, and SMT were associated with worse DSS.

conclusionLarge or multifocal tumors are negative prognostic factors in patients with head and neck CA. S-XRT improved outcomes.

Indexed as

Head and Neck NeoplasmsHemangiosarcomaSkin NeoplasmsCombined Modality TherapyHumansPrognosisProportional Hazards ModelsRetrospective Studiesangiosarcomaradiationsurgery

Identifiers

PMID37272774
PMCPMC11350586
OpenAlexW4379377326

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.