Evidence map›Paper›PMID 37272619›Full record

ArticleeLife2023

Microcephaly-associated protein WDR62 shuttles from the Golgi apparatus to the spindle poles in human neural progenitors.

Claudia Dell'Amico, Marilyn M Angulo Salavarria, Yutaka Takeo, Ichiko Saotome, Maria Teresa Dell'Anno, Maura Galimberti, Enrica Pellegrino, Elena Cattaneo, Angeliki Louvi, Marco Onorati

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Metabolic trajectories in developing human neocortical neurons.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Claudia Dell'AmicoDepartment of Biology, Unit of Cell and Developmental Biology, University of Pisa, Pisa, Italy.ORCID 0000-0002-8234-3423
Marilyn M Angulo SalavarriaDepartment of Biology, Unit of Cell and Developmental Biology, University of Pisa, Pisa, Italy.ORCID 0009-0001-9418-4861
Yutaka TakeoDepartments of Neurosurgery and Neuroscience, Yale School of Medicine, New Haven, United States.ORCID 0009-0009-8198-2870
Ichiko SaotomeDepartments of Neurosurgery and Neuroscience, Yale School of Medicine, New Haven, United States.
Maria Teresa Dell'AnnoFondazione Pisana per la Scienza ONLUS, San Giuliano Terme, Italy.ORCID 0000-0003-1825-671X
Maura GalimbertiDipartimento di Bioscienze, Università degli Studi di Milano, Milan, Italy.
Enrica PellegrinoDepartment of Biology, Unit of Cell and Developmental Biology, University of Pisa, Pisa, Italy.ORCID 0000-0002-3918-2310
Elena CattaneoDipartimento di Bioscienze, Università degli Studi di Milano, Milan, Italy.ORCID 0000-0002-0755-4917
Angeliki LouviDepartments of Neurosurgery and Neuroscience, Yale School of Medicine, New Haven, United States.ORCID 0000-0003-1737-8707
Marco OnoratiDepartment of Biology, Unit of Cell and Developmental Biology, University of Pisa, Pisa, Italy.ORCID 0000-0001-8517-930X
University of Pisa · ITYale University · USUniversity of Milan · ITFondazione Pisa · IT

Funding

Molecular Mechanisms of Primary MicrocephalyR01HD075822 · NICHD · YALE UNIVERSITY · PI LOUVI, ANGELIKI · 2013 to 2017
$1.7M
NICHD NIH HHS R01 HD075822
6 · The paper itself

Abstract

WDR62 is a spindle pole-associated scaffold protein with pleiotropic functions. Recessive mutations in

Indexed as

Cell Cycle ProteinsGolgi ApparatusMicrocephalyNerve Tissue ProteinsSpindle PolesAdolescentChildHumansInduced Pluripotent Stem CellsMaleMitosisCell Cycle ProteinsNerve Tissue ProteinsWDR62 protein, humandisease modelinghumaniPSCsMCPHmicrocephalymouseneural stem cellsneurodevelopmental disordersregenerative medicinestem cellsWDR62

Identifiers

PMID37272619
PMCPMC10241521
OpenAlexW4379375658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.