Evidence map›Paper›PMID 37272551›Full record

ArticleEcotoxicology and environmental safety2023

Potential for cardiac toxicity with methylimidazolium ionic liquids.

Tarek M Abdelghany, Shireen A Hedya, Carol De Santis, Sahar S Abd El-Rahman, Jason H Gill, Noha F Abdelkader, Matthew C Wright

Open access · goldAbstract read
In one paragraph

Article in Ecotoxicology and environmental safety, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Tarek M AbdelghanyInstitute Translational and Clinical Research, Level 4 Leech, Newcastle University, Newcastle Upon Tyne NE2 4HH, United Kingdom; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt; School of Biomedical, Nutritional and Sport Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne NE24HH, United Kingdom.
Shireen A HedyaInstitute Translational and Clinical Research, Level 4 Leech, Newcastle University, Newcastle Upon Tyne NE2 4HH, United Kingdom; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt.
Carol De SantisSchool of Pharmacy, King George VI Building, Newcastle University, Newcastle Upon Tyne NE2 4HH, United Kingdom.
Sahar S Abd El-RahmanFaculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Jason H GillSchool of Pharmacy, King George VI Building, Newcastle University, Newcastle Upon Tyne NE2 4HH, United Kingdom.
Noha F AbdelkaderDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt.
Matthew C WrightInstitute Translational and Clinical Research, Level 4 Leech, Newcastle University, Newcastle Upon Tyne NE2 4HH, United Kingdom. Electronic address: m.c.wright@ncl.ac.uk.
Newcastle University · GBCairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylimidazolium ionic liquids (MILs) are solvent chemicals used in industry. Recent work suggests that MILs are beginning to contaminate the environment and lead to exposure in the general population. In this study, the potential for MILs to cause cardiac toxicity has been examined. The effects of 5 chloride MIL salts possessing increasing alkyl chain lengths (2 C, EMI; 4 C, BMI; 6 C; HMI, 8 C, M8OI; 10 C, DMI) on rat neonatal cardiomyocyte beat rate, beat amplitude and cell survival were initially examined. Increasing alkyl chain length resulted in increasing adverse effects, with effects seen at 10

Indexed as

Ionic LiquidsAnimalsATP Binding Cassette Transporter, Subfamily G, Member 2CardiotoxicityChloridesHumansMiceNeoplasm ProteinsRatsSolventsATP Binding Cassette Transporter, Subfamily G, Member 2ChloridesIonic LiquidsNeoplasm ProteinsSolventsAR42J-B13C8[mim]HeartIonic liquidsMTTTransporter

Identifiers

PMID37272551
PMCPMC10262066
OpenAlexW4312183660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.