Evidence map›Paper›PMID 37272226›Full record

ArticleCancer communications (London, England)2023

Single-cell transcriptomic analysis uncovers intratumoral heterogeneity and drug-tolerant persister in ALK-rearranged lung adenocarcinoma.

Hoi-Hin Kwok, Huiyu Li, Jiashuang Yang, Junyang Deng, Nerissa Chui-Mei Lee, Timmy Wing-Kuk Au, Alva Ko-Yung Sit, Michael Kuan-Yew Hsin, Stephanie Kwai-Yee Ma, Lydia Wai-Ting Cheung and 6 more

Open access · goldAbstract readLetter
In one paragraph

Article in Cancer communications (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Hoi-Hin KwokDepartment of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, P. R. China.ORCID 0000-0002-6902-8402
Huiyu LiNancy B. and Jake L. Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jiashuang YangDepartment of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, P. R. China.
Junyang DengDepartment of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, P. R. China.
Nerissa Chui-Mei LeeDepartment of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, P. R. China.
Timmy Wing-Kuk AuCardiothoracic Surgical Department, Queen Mary Hospital, Hong Kong SAR, P. R. China.
Alva Ko-Yung SitCardiothoracic Surgical Department, Queen Mary Hospital, Hong Kong SAR, P. R. China.
Michael Kuan-Yew HsinCardiothoracic Surgical Department, Queen Mary Hospital, Hong Kong SAR, P. R. China.
Stephanie Kwai-Yee MaSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.
Lydia Wai-Ting CheungSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.
Luc GirardNancy B. and Jake L. Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Junya FujimotoDepartment of Translational Molecular Pathology, Division of Pathology/Lab Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Ignacio Ivan WistubaDepartment of Translational Molecular Pathology, Division of Pathology/Lab Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Boning GaoNancy B. and Jake L. Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
John Dorrance MinnaNancy B. and Jake L. Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
David Chi-Leung LamDepartment of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, P. R. China.ORCID 0000-0002-0004-2660
University of Hong Kong · HKSouthwestern Medical CenterQueen Mary Hospital · CNThe University of Texas MD Anderson Cancer Center · US

Funding

UNIVERSITY OF TEXAS--SPORE IN LUNG CANCERP50CA070907 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HEYMACH, JOHN V., MINNA, JOHN D. · 1996 to 2024
$57.4M
NCI NIH HHS P50 CA070907
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenocarcinoma of LungLung NeoplasmsHumansReceptor Protein-Tyrosine KinasesTranscriptomeReceptor Protein-Tyrosine Kinases

Identifiers

PMID37272226
PMCPMC10397560
OpenAlexW4379376648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.