ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2023
[Intestinal and pharyngeal microbiota in early neonates: an analysis based on high-throughput sequencing].
Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 2 citations in OpenAlex.
- The avian respiratory microenvironment-immune nexus: A three-dimensional regulation model from local homeostasis to systemic defense.Poultry science · 2026Article
- Comparison of intestinal and pharyngeal microbiota in preterm infants on the first day of life and the characteristics of pharyngeal microbiota in infants delivered by cesarean section or vaginally.Frontiers in pediatrics · 2024Article
- Neonatal body composition, salivary feeding gene expression, and feeding outcomes in infants of diabetic mothers.Frontiers in clinical diabetes and healthcare · 2024Article
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6 authors at 1 institution in 1 country.
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Abstract
objectivesTo investigate the distribution characteristics and correlation of intestinal and pharyngeal microbiota in early neonates.
methodsFull-term healthy neonates who were born in Shanghai Pudong New Area Maternal and Child Health Hospital from September 2021 to January 2022 and were given mixed feeding were enrolled. The 16S rRNA sequencing technique was used to analyze the stool and pharyngeal swab samples collected on the day of birth and days 5-7 after birth, and the composition and function of intestinal and pharyngeal microbiota were analyzed and compared.
resultsThe diversity analysis showed that the diversity of pharyngeal microbiota was higher than that of intestinal microbiota in early neonates, but the difference was not statistically significant (
conclusionsThe composition and diversity of intestinal and pharyngeal microbiota of neonates are not significantly different at birth. The microbiota of these two ecological niches begin to differentiate and gradually exhibit distinct functions over time.
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