ArticleBMC medical imaging2023
Evaluation of liver function using Gd-EOB-DTPA-enhanced MRI with T1 mapping.
Article in BMC medical imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Gadoxetic Acid-Enhanced T1 Mapping Enables Transporter-Mediated Molecular Imaging of Liver Functional Reserve.Biomedicines · 2026Article
- Gd-EOB-DTPA-enhanced MRI in the diagnosis of intrahepatic cholestasis in mice: an experimental study.BMC medical imaging · 2026Article
- Functional Avoidance Liver 4π Stereotactic Body Radiation Therapy Informed by Quantitative Gadoxetic Acid Contrast-Enhanced Magnetic Resonance T1 Mapping.International journal of radiation oncology, biology, physics · 2026Article
- Does Gd-EOB-DTPA-enhanced T1 mapping have a role in the staging of fibrosis and inflammation in autoimmune hepatitis? A prospective study.Abdominal radiology (New York) · 2026Article
- Extent of Embolization as an Independent Prognostic Factor in Superselective Conventional Transarterial Chemoembolization for Hepatocellular Carcinoma.Journal of hepatocellular carcinoma · 2026Article
- Intrahepatic diffuse periportal hyperintensity patterns on hepatobiliary phase of gadoxetate-enhanced MRI: a non-invasive imaging biomarker for clinical stratification of liver injury.Abdominal radiology (New York) · 2025Article
- Automated quantification of T1 and T2 relaxation times in liver mpMRI using deep learning: a sequence-adaptive approach.European radiology experimental · 2025Article
- Radiomic analysis using T1 mapping in gadoxetic acid disodium-enhanced MRI for liver function assessment.BMC medical imaging · 2025Article
- Evaluation of liver function using hepatocyte uptake and T1 mapping indices in gadoxetic acid-enhanced magnetic resonance imaging: correlation with the albumin-bilirubin grading system.Quantitative imaging in medicine and surgery · 2025Article
- Free-breathing, fat-corrected TMagnetic resonance in medicine · 2024Article
- Magnetic resonance imaging T1 mapping of the liver, pancreas and spleen in children.Abdominal radiology (New York) · 2024Article
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10 authors.
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Abstract
purposeTo evaluate the value of MRI T1 mapping with Gd-EOB-DTPA for assessing liver function.
methodsSeventy-two patients who underwent Gd-EOB-DTPA-enhanced MRI for focal liver lesions at Beijing Friendship Hospital from August 2020 to March 2022 were prospectively enrolled, and variable-flip-angle T1 mapping was performed before and 20 min after enhancement. The Child-Pugh (C-P) score and albumin-bilirubin (ALBI) grade of liver function were assessed using the clinical data of the patients. Correlation analysis was used to evaluate the correlation between T1 mapping parameters and liver function grading and laboratory tests. Nonparametric tests were used to compare the differences among different liver function groups. The liver function classification efficiency of each image index was evaluated with receiver operating characteristic (ROC) curves.
resultsT1post was positively correlated with the C-P grade and the ALBI grade (r = 0.717 and r = 0.652). ΔT1 was negatively correlated with the C-P grade and the ALBI grade (r = -0.790 and r = -0.658). T1post and ΔT1 significantly differed among different liver function grades (p < 0.05). For the C-P grade, T1post and ΔT1 were significantly different between each pair of groups (p < 0.05), and ΔT1 had a better diagnostic efficiency than T1post. For the ALBI grade, ΔT1 and T1post were significantly different between the NLF and ALBI1 groups (p < 0.05), and ΔT1 had a better diagnostic efficacy than T1post. T1post significantly differed between the ALBI1 and ALBI2 + 3 groups (p < 0.05), while ΔT1 had a weak ability to differentiate between these two groups.
conclusionT1post and ΔT1 were strongly correlated with the two liver function grades and can be noninvasive imaging indexes for evaluating liver function.
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