Evidence map›Paper›PMID 37271212›Full record

ArticleKorean journal of radiology2023

Pretherapy

Mei-Fang Cheng, Yue Leon Guo, Ruoh-Fang Yen, Yen-Wen Wu, Hsiu-Po Wang

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mei-Fang ChengDepartment of Nuclear Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-9359-0606
Yue Leon GuoInstitute of Environmental and Occupational Health Sciences, National Taiwan University, Taipei, Taiwan.ORCID 0000-0002-8530-4809
Ruoh-Fang YenDepartment of Nuclear Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0003-1648-6482
Yen-Wen WuDepartment of Nuclear Medicine, Cardiovascular Medical Center, Far Eastern Memorial Hospital, New Taipei, Taiwan.ORCID 0000-0003-1520-1166
Hsiu-Po WangDepartment of Internal Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan. wanghp@ntu.edu.tw.ORCID 0000-0002-7741-9315
National Taiwan University · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate whether the levels of inflammation detected by MATERIALS AND

methodsThis prospective study analyzed pretherapy FDG PET/CT images from 48 patients (mean age, 63 ± 12.9 years; 45 males and 3 females) diagnosed with IgG4-RD between September 2008 and February 2018, who subsequently received standard induction steroid therapy as the first-line treatment. Multivariable Cox proportional hazards models were used to identify the potential prognostic factors associated with relapse-free survival (RFS).

resultsThe median follow-up time for the entire cohort was 1913 days (interquartile range [IQR], 803-2929 days). Relapse occurred in 81.3% (39/48) patients during the follow-up period. The median time to relapse was 210 days (IQR, 140-308 days) after completion of standardized induction steroid therapy. Among the 17 parameters analyzed, Cox proportional hazard analysis identified whole-body total lesion glycolysis (WTLG) > 600 on FDG-PET as an independent risk factor for disease relapse (median RFS, 175 vs. 308 days; adjusted hazard ratio, 2.196 [95% confidence interval: 1.080-4.374];

conclusionWTLG on pretherapy FDG PET/CT was the only significant factor associated with RFS in IgG-RD patients receiving standard steroid induction therapy.

Indexed as

Fluorodeoxyglucose F18Immunoglobulin G4-Related DiseaseAgedFemaleHumansMaleMiddle AgedPositron-Emission TomographyPositron Emission Tomography Computed TomographyPrognosisProspective StudiesRadiopharmaceuticalsRetrospective StudiesSteroidsFluorodeoxyglucose F18RadiopharmaceuticalsSteroidsIgG4-RDPET/CTRelapse-free survivalTherapy

Identifiers

PMID37271212
PMCPMC10248362
OpenAlexW4378639435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.