Evidence map›Paper›PMID 37270934›Full record

ArticleDrug and alcohol dependence2023

Adolescent simultaneous use of alcohol and marijuana by trends in cigarette and nicotine vaping from 2000 to 2020.

Katherine M Keyes, Victoria Joseph, Navdep Kaur, Noah T Kreski, Qixuan Chen, Silvia S Martins, Deborah Hasin, Mark Olfson, Pia M Mauro

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katherine M KeyesDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA. Electronic address: Kmk2104@columbia.edu.
Victoria JosephDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Navdep KaurDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Noah T KreskiDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Qixuan ChenDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.
Silvia S MartinsDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Deborah HasinDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA; New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York, USA.
Mark OlfsonDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA; New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York, USA.
Pia M MauroDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.

Funding

RESEARCH TRAINING PROGRAM IN PSYCHIATRIC EPIDEMIOLOGYT32MH013043 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Katherine M. Keyes · 1985 to 2026
$11.7M
Columbia Injury Control Research CenterR49CE002096 · CE · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LI, GUOHUA · 2012 to 2018
$5.5M
As adolescent substance use declines, internalizing symptoms increase: identifying high-risk substance using groups and the role of social media, parental supervision, and unsupervised timeR01DA048853 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEYES, KATHERINE M. · 2019 to 2023
$2.0M
Multi-level associations between medical marijuana laws and substance use disorder treatmentK01DA045224 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAURO, PIA M. · 2018 to 2022
$878k
ACL HHS R49CE002096NCIPC CDC HHS R49 CE002096NIDA NIH HHS K01 DA045224NIDA NIH HHS R01 DA048853NIMH NIH HHS T32 MH013043
6 · The paper itself

Abstract

backgroundSimultaneous alcohol and marijuana (SAM) use is associated with adverse consequences for youth. While SAM use is overall declining among youth, prior studies indicate increasing marijuana use among US adolescents who ever used cigarettes, suggesting possible moderation of the alcohol-marijuana relationship by cigarette use.

methodsWe included 43,845 12-th grade students participating in Monitoring the Future data (2000-2020). A 5-level alcohol/marijuana measure was used, including past-year SAM, alcohol-only, marijuana-only, non-simultaneous alcohol and marijuana, or no use. Multinomial logistic regressions estimated associations between time periods (categorized based on sample size: 2000-2005, 2006-2009, 2010-2014, 2015-2020) and the 5-level alcohol/marijuana measure. Models adjusted for sex, race, parental education and survey mode and included interactions of time periods and lifetime cigarette or vaped nicotine use.

resultsWhile overall SAM among 12th graders decreased from 23.65% to 18.31% between 2000 and 2020, SAM increased among students who never used cigarettes or vaped nicotine (from 5.42% to 7.03%). Among students who ever used cigarettes or vaped nicotine, SAM increased from 39.2% in 2000-2005-44.1% in 2010-2014 then declined to 37.8% in 2015-2020. Adjusted models controlling for demographics indicated that among students with no lifetime cigarette or vaped nicotine use, students in 2015-2020 had 1.40 (95% C.I. 1.15-1.71) times the odds of SAM, and 5.43 (95% C.I. 3.63-8.12) times the odds of marijuana-only (i.e., no alcohol use) compared to students who used neither in 2000-2005. Alcohol-only declined over time in both students who ever and never used cigarettes or nicotine vape products.

conclusionParadoxically, while SAM declined in the overall adolescent US population, the prevalence of SAM increased among students who have never smoked cigarettes or vaped nicotine. This effect arises because of a substantial decline in the prevalence of cigarette smoking; smoking is a risk factor for SAM, and fewer students smoke. Increases in vaping are offsetting these changes, however. Preventing adolescent use of cigarettes and nicotine vaped products could have extended benefits for other substance use, including SAM.

Indexed as

CannabisElectronic Nicotine Delivery SystemsHallucinogensMarijuana UseSubstance-Related DisordersTobacco ProductsVapingAdolescentEthanolHumansNicotineEthanolHallucinogensNicotineAlcoholCigarettesMarijuanaNicotine vapingSimultaneous use

Identifiers

PMID37270934
PMCPMC10348405

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.