Evidence map›Paper›PMID 37270570›Full record

ArticleNPJ biofilms and microbiomes2023

Dissecting the impact of dietary fiber type on atherosclerosis in mice colonized with different gut microbial communities.

Evan R Hutchison, Kazuyuki Kasahara, Qijun Zhang, Eugenio I Vivas, Tzu-Wen L Cross, Federico E Rey

Open access · goldAbstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  17. Tunable control ofGut microbes
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Evan R HutchisonMicrobiology Doctoral Training Program, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-3251-0120
Kazuyuki KasaharaDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0003-3303-7216
Qijun ZhangDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-1003-7355
Eugenio I VivasDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.
Tzu-Wen L CrossDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.
Federico E ReyDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA. ferey@wisc.edu.ORCID 0000-0002-0239-7780
University of Wisconsin–Madison · US

Funding

Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
TRAINING IN NUTRITIONT32DK007665 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI GUY E GROBLEWSKI, Chi- Liang Eric Yen · 1993 to 2026
$9.2M
Systems Genetics Dissection of Non-alcoholic SteatohepatitisR01DK117850 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Aldons Jake Lusis · 2019 to 2026
$4.6M
Model-guided design of next-generation bacterial therapeutics to treat cardiovascular diseaseR01EB030340 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI REY, FEDERICO E, ROMERO, PHILIP ANTHONY · 2020 to 2023
$2.8M
Establishing mechanistic links between the gut microbiome and atherosclerosisR01HL148577 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LUSIS, ALDONS JAKE, REY, FEDERICO E · 2020 to 2023
$2.6M
Gut microbiota and metabolite interactions in atherosclerosisR01HL144651 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LUSIS, ALDONS JAKE, REY, FEDERICO E · 2019 to 2022
$2.6M
NHLBI NIH HHS R01 HL144651NHLBI NIH HHS R01 HL148577NHLBI NIH HHS T32 HL007936NIBIB NIH HHS R01 EB030340NIDDK NIH HHS R01 DK117850NIDDK NIH HHS T32 DK007665
6 · The paper itself

Abstract

Dietary fiber consumption has been linked with improved cardiometabolic health, however, human studies have reported large interindividual variations in the observed benefits. We tested whether the effects of dietary fiber on atherosclerosis are influenced by the gut microbiome. We colonized germ-free ApoE

Indexed as

AtherosclerosisMicrobiotaAnimalsButyratesCelluloseDietary FiberGlucosamineHumansMiceButyratesCelluloseDietary FiberGlucosamine

Identifiers

PMID37270570
PMCPMC10239454
OpenAlexW4379206979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.