ArticleNature communications2023
Multi-compartmental MOF microreactors derived from Pickering double emulsions for chemo-enzymatic cascade catalysis.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 96 citations in OpenAlex.
- On-Demand Viscosity Gradients Turn Nanoliter Droplets into Programmable Sources of Enriched Picoliter Droplets.Journal of the American Chemical Society · 2026Article
- Nanomaterial Integration at Liquid-Liquid Interfaces for Green Catalysis.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- A hierarchical dual-lock mechanism empowered epifluidic patch for rapid glucose feedback in exercise-induced sweating.Mikrochimica acta · 2026Article
- Hierarchical Oil-Water-Oil Pickering Double Emulsions Stabilized by Tubular Nanoparticles.Journal of the American Chemical Society · 2026Article
- Assembling a single active pocket from enzyme and metal modules for simultaneously catalyzing oxidation-reduction cascades.Nature communications · 2026Article
- Boosting Stabilized Pickering Emulsion via Janus Materials for Efficient Interfacial Photoreforming Hydrogen Evolution.ACS omega · 2026Article
- Sequential Optimization of Multivariate Metal-Organic Framework Based Biocatalysis.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Lipid-Metal-Organic Framework Colloidosomes for Multimodal Encapsulation and Pollutant Capture.Computational and structural biotechnology journal · 2026Article
- Ultrafast and scalable synthesis of enzyme-metal hybrid catalysts in evaporating microdroplets.Science advances · 2025Article
- Ionic organic cage as a versatile platform for immobilizing chemical and enzymatic sites for chemoenzymatic catalysis.Nature communications · 2025Article
- Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues.Nature chemistry · 2025Article
- Enhancing Multi-Enzyme Cascade Activity in Metal-Organic Frameworks via Controlled Enzyme Encapsulation.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Host-Guest Synergy of Metal-Organic Frameworks for Enhanced Near-Infrared Ultrafast Laser Responsiveness.ACS central science · 2025Article
- Stimuli-responsive Zn(ii) complexes showing the structural conversion and on/off switching of catalytic properties.RSC advances · 2024Article
- Photo-modulated activation of organic bases enabling microencapsulation and on-demand reactivity.Nature communications · 2024Article
- Boosting Enzyme Activity in Enzyme Metal-Organic Framework Composites.Chem & bio engineering · 2024Review
- Opportunities and Challenges of Metal-Organic Framework Micro/Nano Reactors for Cascade Reactions.JACS Au · 2023Review
- Application and Development Prospect of Nanoscale Iron Based Metal-Organic Frameworks in Biomedicine.International journal of nanomedicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioinspired multi-compartment architectures are desired in synthetic biology and metabolic engineering, as credited by their cell-like structures and intrinsic ability of assembling catalytic species for spatiotemporal control over cascade reactions like in living systems. Herein, we describe a general Pickering double emulsion-directed interfacial synthesis method for the fabrication of multicompartmental MOF microreactors. This approach employs multiple liquid-liquid interfaces as a controllable platform for the self-completing growth of dense MOF layers, enabling the microreactor with tailor-made inner architectures and selective permeability. Importantly, simultaneous encapsulation of incompatible functionalities, including hydrophilic enzyme and hydrophobic molecular catalyst, can be realized in a single MOF microreactor for operating chemo-enzymatic cascade reactions. As exemplified by the Grubb' catalyst/CALB lipase driven olefin metathesis/ transesterification cascade reaction and glucose oxidase (GOx)/Fe-porphyrin catalyzed oxidation reaction, the multicompartmental microreactor exhibits 2.24-5.81 folds enhancement in cascade reaction efficiency in comparison to the homogeneous counterparts or physical mixture of individual analogues, due to the restrained mutual inactivation and substrate channelling effects. Our study prompts further design of multicompartment systems and the development of artificial cells capable of complex cellular transformations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.