Evidence map›Paper›PMID 37270488›Full record

ArticleBMC oral health2023

Artificial intelligence in the diagnosis of dental diseases on panoramic radiographs: a preliminary study.

Junhua Zhu, Zhi Chen, Jing Zhao, Yueyuan Yu, Xiaojuan Li, Kangjian Shi, Fan Zhang, Feifei Yu, Keying Shi, Zhe Sun and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Junhua ZhuSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Zhi ChenSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Jing ZhaoSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Yueyuan YuSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Xiaojuan LiCollege of Computer Science and Technology, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Kangjian ShiCollege of Computer Science and Technology, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Fan ZhangCollege of Computer Science and Technology, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Feifei YuSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Keying ShiSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Zhe SunSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Nengjie LinSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Yuanna ZhengSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. zyn218@126.com.
Zhejiang Chinese Medical University · CNZhejiang University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) has been introduced to interpret the panoramic radiographs (PRs). The aim of this study was to develop an AI framework to diagnose multiple dental diseases on PRs, and to initially evaluate its performance.

methodsThe AI framework was developed based on 2 deep convolutional neural networks (CNNs), BDU-Net and nnU-Net. 1996 PRs were used for training. Diagnostic evaluation was performed on a separate evaluation dataset including 282 PRs. Sensitivity, specificity, Youden's index, the area under the curve (AUC), and diagnostic time were calculated. Dentists with 3 different levels of seniority (H: high, M: medium, L: low) diagnosed the same evaluation dataset independently. Mann-Whitney U test and Delong test were conducted for statistical analysis (ɑ=0.05).

resultsSensitivity, specificity, and Youden's index of the framework for diagnosing 5 diseases were 0.964, 0.996, 0.960 (impacted teeth), 0.953, 0.998, 0.951 (full crowns), 0.871, 0.999, 0.870 (residual roots), 0.885, 0.994, 0.879 (missing teeth), and 0.554, 0.990, 0.544 (caries), respectively. AUC of the framework for the diseases were 0.980 (95%CI: 0.976-0.983, impacted teeth), 0.975 (95%CI: 0.972-0.978, full crowns), and 0.935 (95%CI: 0.929-0.940, residual roots), 0.939 (95%CI: 0.934-0.944, missing teeth), and 0.772 (95%CI: 0.764-0.781, caries), respectively. AUC of the AI framework was comparable to that of all dentists in diagnosing residual roots (p > 0.05), and its AUC values were similar to (p > 0.05) or better than (p < 0.05) that of M-level dentists for diagnosing 5 diseases. But AUC of the framework was statistically lower than some of H-level dentists for diagnosing impacted teeth, missing teeth, and caries (p < 0.05). The mean diagnostic time of the framework was significantly shorter than that of all dentists (p < 0.001).

conclusionsThe AI framework based on BDU-Net and nnU-Net demonstrated high specificity on diagnosing impacted teeth, full crowns, missing teeth, residual roots, and caries with high efficiency. The clinical feasibility of AI framework was preliminary verified since its performance was similar to or even better than the dentists with 3-10 years of experience. However, the AI framework for caries diagnosis should be improved.

Indexed as

Dental CariesToothTooth, ImpactedArtificial IntelligenceHumansRadiography, PanoramicArtificial intelligence (AI)Dental diseaseDiagnosisPanoramic radiographPreliminary reading

Identifiers

PMID37270488
PMCPMC10239110
OpenAlexW4379259886

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.