SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2023
Robotic-assisted mechanically aligned total knee arthroplasty does not lead to better clinical and radiological outcomes when compared to conventional TKA: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Comparative pain relief and functional outcomes following robotic-assisted versus conventional total knee arthroplasty: a GRADE-assessed meta-analysis with meta-regression of randomized controlled trials.Journal of robotic surgery · 2026Pooled it
- Improved alignment accuracy but similar early clinical outcomes with NAVIO imageless robotic-assisted vs. conventional total knee arthroplasty: a meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Comparison of robotic-assisted total knee arthroplasty: an updated systematic review and meta-analysis.Journal of robotic surgery · 2024Pooled it
- Better radiological outcomes but equal clinical function of a novel knee arthroplasty robot system: a prospective randomized controlled trial.International orthopaedics · 2025Trial
- Early Radiographic and Clinical Outcomes of Robotic-arm-assisted versus Conventional Total Knee Arthroplasty: A Multicenter Randomized Controlled Trial.Orthopaedic surgery · 2024Trial
- A historical journey through total knee arthroplasty: the evolutionary milestones.International orthopaedics · 2026Review
- Comparison of early postoperative activity-related pain burden after conventional, navigation-assisted, and robotic-assisted total knee arthroplasty: a retrospective cohort study based on 24-72 h pain area under the curve.Journal of robotic surgery · 2026Article
- Robotic Assistance for Low-Volume Total Knee Arthroplasty Surgeons Is Associated With Comparable Perioperative Outcomes Related to Those of High-Volume Surgeons Using Conventional Techniques.Arthroplasty today · 2026Article
- Intentional asymmetric balancing in robotic-assisted valgus TKA: Early outcomes and intraoperative laxity changes.Journal of experimental orthopaedics · 2026Article
- Article
- Early outcomes and the learning curve of two domestically produced surgical robot systems with different operational philosophies for total knee arthroplasty.Journal of robotic surgery · 2026Article
- Analysis of the clinical efficacy of robot-assisted left total knee arthroplasty performed by surgeons with varying levels of experience.Journal of robotic surgery · 2026Article
- How Likely Do Patients After Total Knee Arthroplasty with a Posterior-Stabilized Knee System Meet Their Desired Sport Activity Level?Journal of clinical medicine · 2026Article
- Clinical and radiographic outcomes of double-triangle locking compression plate (DT-LCP) versus T-shaped locking compression plate (T-LCP) in medial open-wedge high tibial osteotomy: a follow-up study of over 5 years.Journal of orthopaedic surgery and research · 2026Article
- TOURNIQUET USE DOES NOT AFFECT BLEEDING AND SURGICAL TIME IN ROBOTIC-ASSISTED KNEE ARTHROPLASTY.Acta ortopedica brasileira · 2026Article
- Correlation between preoperative nutritional status and postoperative clinical outcomes in patients undergoing artificial hip and knee replacement.American journal of translational research · 2026Article
- Flexion gap discrepancy drives femoral rotational adjustment in robot-assisted TKA: a CPAK-Based phenotypic analysis.BMC musculoskeletal disorders · 2025Article
- Real-World Outcomes of Robotic Total Knee Arthroplasty: Five Years' Experience in a Non-Academic Center.Journal of personalized medicine · 2025Article
- Robotic vs. conventional total knee arthroplasty over two decades: Evolving trends toward personalised alignment without significant clinical superiority in predominantly mild varus deformity-A systematic review of RCTs.Journal of experimental orthopaedics · 2025Review
- Depressive symptoms influence progression to total knee arthroplasty in patients with early knee osteoarthritis: Evidence from the Osteoarthritis Initiative database.Journal of experimental orthopaedics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRobotic-assisted total knee arthroplasty (R-TKA) has emerged as an alternative to improve the results of the conventional manual TKA (C-TKA). The aim of this study was to analyse the high-level studies comparing R-TKA and C-TKA in terms of clinical outcomes, radiological results, perioperative parameters, and complications.
methodsThe literature search was conducted on three databases (PubMed, Cochrane, and Web of Science) on 1 February 2023 according to the guidelines for Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Inclusion criteria were: randomized controlled trials (RCTs), written in English language, published in the last 15 years, focusing on the comparison of C-TKA and R-TKA results. The quality of each article was assessed using the Cochrane risk-of-bias tool for randomized trials version 2 (RoB 2). The statistical analysis was carried out using random effects (DerSimonian & Laird) for weighted mean difference (MD) of the continuous variables and Peto method for odds ratios of the dichotomous variables.
resultsAmong the 2905 articles retrieved, 14 RCTs on 12 series of patients treated with mechanically aligned implants were included. A total of 2255 patients (25.1% males and 74.9% females; mean age 62.9 ± 3.0; mean BMI 28.1 ± 1.3) were analysed. The results of this systematic review and meta-analysis showed that R-TKA did not provide overall superior results compared to C-TKA in mechanically aligned implants in terms of clinical and radiological outcomes. R-TKA showed longer operative time (MD = 15.3 min, p = 0.004) and similar complication rates compared to C-TKA. A statistically significant difference in favour of R-TKA was found in the posterior-stabilized subgroup in terms of radiological outcomes (hip-knee-ankle angle MD = 1.7, p < 0.001) compared to C-TKA, although without resulting in appreciable difference of clinical outcomes.
conclusionR-TKA did not provide overall superior results compared to C-TKA in terms of clinical and radiological outcomes, showing longer operative time and similar complication rates. LEVEL OF EVIDENCE: Level I.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.