Evidence map›Paper›PMID 37270030›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2023

Perspective: Council for Responsible Nutrition Science in Session. Optimizing Health with Nutrition-Opportunities, Gaps, and the Future.

Emily Ho, Victoria J Drake, Alexander J Michels, Yasmeen M Nkrumah-Elie, LaVerne L Brown, Jonathan M Scott, John W Newman, Barbara Shukitt-Hale, Amala Soumyanath, Floyd H Chilton and 3 more

Abstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Emily HoLinus Pauling Institute, Oregon State University, Corvallis, Oregon; Nutrition Program, College of Public Health and Human Sciences, Oregon State University, Corvallis, Oregon. Electronic address: emily.ho@oregonstate.edu.
Victoria J DrakeLinus Pauling Institute, Oregon State University, Corvallis, Oregon.
Alexander J MichelsLinus Pauling Institute, Oregon State University, Corvallis, Oregon.
Yasmeen M Nkrumah-ElieChromaDex External Research Program, Los Angeles, California.
LaVerne L BrownNational Institutes of Health, Office of Dietary Supplements, Bethesda, Maryland.
Jonathan M ScottConsortium for Health and Military Performance, Department of Military and Emergency Medicine, F. Edward Hébert School of Medicine, Uniformed Services University, Bethesda, Maryland.
John W NewmanUnited States Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center, Davis, California.
Barbara Shukitt-HaleUnited States Department of Agriculture, Agricultural Research Service, Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts.
Amala SoumyanathBENFRA Botanical Dietary Supplements Research Center, Department of Neurology, Oregon Health and Science University, Portland, Oregon.
Floyd H ChiltonCenter for Precision Nutrition and Wellness, University of Arizona, Tucson, Arizona; School of Nutritional Sciences and Wellness, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona.
Stephen R LindemannWhistler Center for Carbohydrate Research, Department of Food Science, Purdue University, West Lafayette, Indiana.
Andrew ShaoChromaDex External Research Program, Los Angeles, California.
Susan Hazels MitmesserPharmavite, LLC, West Hills, California.

Funding

Mechanisms underlying the cognitive effects of Centella asiatica water extract and constituent compounds in the 5xFAD mouse model of Alzheimer's DiseaseU19AT010829 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI SOUMYANATH, AMALA · 2020 to 2024
$6.1M
Role of PUFA-Gene Interactions in Health DisparitiesR01AT008621 · NCCIH · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI FLOYD H CHILTON, Susan Schembre · 2016 to 2026
$5.4M
Mechanisms and active compounds in the cognitive effects of Centella asiaticaR01AT008099 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI SOUMYANATH, AMALA · 2014 to 2018
$2.2M
Carbohydrate Structure Controls on Human Gut Microbial EcologyR35GM133634 · NIGMS · PURDUE UNIVERSITY · PI LINDEMANN, STEPHEN ROBERT · 2019 to 2023
$1.9M
Biological signatures of the cognitive effects of Centella asiaticaR61AT009628 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI QUINN, JOSEPH F, SOUMYANATH, AMALA · 2017 to 2019
$522k
NCCIH NIH HHS R01 AT008099NCCIH NIH HHS R01 AT008621NCCIH NIH HHS U19 AT010829NIGMS NIH HHS R35 GM133634
6 · The paper itself

Abstract

Achieving optimal health is an aspirational goal for the population, yet the definition of health remains unclear. The role of nutrition in health has evolved beyond correcting malnutrition and specific deficiencies and has begun to focus more on achieving and maintaining 'optimal' health through nutrition. As such, the Council for Responsible Nutrition held its October 2022 Science in Session conference to advance this concept. Here, we summarize and discuss the findings of their Optimizing Health through Nutrition - Opportunities and Challenges workshop, including several gaps that need to be addressed to advance progress in the field. Defining and evaluating various indices of optimal health will require overcoming these key gaps. For example, there is a strong need to develop better biomarkers of nutrient status, including more accurate markers of food intake, as well as biomarkers of optimal health that account for maintaining resilience-the ability to recover from or respond to stressors without loss to physical and cognitive performance. In addition, there is a need to identify factors that drive individualized responses to nutrition, including genotype, metabotypes, and the gut microbiome, and to realize the opportunity of precision nutrition for optimal health. This review outlines hallmarks of resilience, provides current examples of nutritional factors to optimize cognitive and performance resilience, and gives an overview of various genetic, metabolic, and microbiome determinants of individualized responses.

Indexed as

Gastrointestinal MicrobiomeNutritional SciencesBiomarkersHumansNutritional StatusBiomarkerscognitionindividual metabolic variabilitymicrobiomenutrient–gene interactionsnutritionoptimal healthprecision healthresilience

Identifiers

PMID37270030
PMCPMC10509435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.