Evidence map›Paper›PMID 37269765›Full record

ReviewInternational journal of surgery case reports2023

IL-6 as a predictor of survival rate in liver metastatic breast cancer patients with Covid-19 infection: A case series.

Dea Alberta Setiawati, Widyanti Soewoto, Ikhdin Radiamin Saadhi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of surgery case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dea Alberta SetiawatiResident of Surgery Department, Sebelas Maret University, Dr. Moewardi General Hospital, Surakarta, Central Java, Indonesia. Electronic address: dea.alberta@gmail.com.
Widyanti SoewotoOncology Surgeon, Department of Surgery, Sebelas Maret University, Dr. Moewardi General Hospital, Surakarta, Central Java, Indonesia. Electronic address: anti.widyanti@gmail.com.
Ikhdin Radiamin SaadhiResident of Surgery Department, Sebelas Maret University, Dr. Moewardi General Hospital, Surakarta, Central Java, Indonesia. Electronic address: misterikhdin@gmail.com.
Sebelas Maret University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and importance: Breast cancer is the most common type of cancer in women, with 30 % being metastatic breast cancer. Cancer is known to be a comorbid Covid-19 infection. Interleukin-6 (IL-6) is one of the findings of inflammatory activity due to Covid-19 infection. We report IL-6 levels as a prognostic factor for survival rate in patients with liver metastatic breast cancer. Case presentation: We report five cases of liver metastatic breast cancer with various types of primary breast cancer. All patients are infected with Covid-19. IL-6 levels were reported to be elevated in all five patients. All patients were treated according to the national guidelines for the care of Covid-19 patients. All patients are reported to have deceased after being treated for Covid-19 infection. Clinical discussion: Metastatic breast cancer has a low prognostic rate. Cancer has been recognized as one of the comorbidities and increases the severity and mortality of Covid-19 infection. Elevated levels of IL-6 are caused by an immune response to infection, and can worsen the outcome of breast cancer patients. Changes in IL-6 levels implicate the survival rate of metastatic breast cancer patients and outcomes during the treatment of Covid-19 infection. Conclusion: Elevated levels of IL-6 can be a prognostic factor of the survival rate of metastatic breast cancer patients during the treatment of Covid-19 infection.

Indexed as

Breast CancerCovid-19Liver metastatic breast CancerPrognosisSurvival rate

Identifiers

PMID37269765
PMCPMC10208658
OpenAlexW4378070776

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.