Evidence map›Paper›PMID 37269332›Full record

ArticleActa neurochirurgica2023

Epithelioid glioblastoma diagnosed 70 years after craniofacial radiotherapy.

Abdulgadir Bugdadi, Mohamed Aziz Cherif, Gokoulakrichenane Loganadane, Pierre Brugières, Amel Marniche, Emmanuel Itti, Yazid Belkacemi, Arnault Tauziède-Espariat, Stephane Palfi, Suhan Senova

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abdulgadir BugdadiDepartment of Neurosurgery, INSERM Laboratory of Translational Neuropsychiatry, IMRB, Université Paris Est Créteil, Henri-Mondor University Hospital, Assistance Publique des Hôpitaux de Paris, Creteil, France.
Mohamed Aziz CherifDepartment of Radiotherapy, Henri-Mondor University Hospital, Creteil, France.
Gokoulakrichenane LoganadaneDepartment of Radiotherapy, Henri-Mondor University Hospital, Creteil, France.
Pierre BrugièresDepartment of Neuroradiology, Henri-Mondor University Hospital, Creteil, France.
Amel MarnicheDepartment of Neurosurgery, INSERM Laboratory of Translational Neuropsychiatry, IMRB, Université Paris Est Créteil, Henri-Mondor University Hospital, Assistance Publique des Hôpitaux de Paris, Creteil, France.
Emmanuel IttiDepartment of Nuclear Medicine, Henri-Mondor University Hospital, Creteil, France.
Yazid BelkacemiDepartment of Radiotherapy, Henri-Mondor University Hospital, Creteil, France.
Arnault Tauziède-EspariatDepartment of Neuropathology, Sainte Anne Hospital, Paris, France.
Stephane PalfiDepartment of Neurosurgery, INSERM Laboratory of Translational Neuropsychiatry, IMRB, Université Paris Est Créteil, Henri-Mondor University Hospital, Assistance Publique des Hôpitaux de Paris, Creteil, France.
Suhan SenovaDepartment of Neurosurgery, INSERM Laboratory of Translational Neuropsychiatry, IMRB, Université Paris Est Créteil, Henri-Mondor University Hospital, Assistance Publique des Hôpitaux de Paris, Creteil, France. yann.senova@aphp.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors report a rare case of most likely radiation-induced glioma (RIG) with epithelioid features and the presence of molecular features consistent with RIG. This occurred 70 years after craniofacial brachytherapy. Such a late development of radiation-induced glioblastoma (RIGBM) and the advanced age of presentation for an epithelioid glioblastoma are both unique in the literature. Despite not receiving the full course of adjuvant chemotherapy after surgery and radiotherapy, the patient displayed no signs of recurrence during a 5-year follow-up. RIGBM should be further studied to reveal potential unique clinical and molecular characteristics, as well as to better predict survival and treatment response.

Indexed as

BrachytherapyBrain NeoplasmsGlioblastomaGliomaHumansNeoplasm Recurrence, LocalBrachytherapyEpithelioid glioblastomaLatency-periodRadiation induced gliomaRadiotherapy

Identifiers

PMID37269332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.