Evidence map›Paper›PMID 37268922›Full record

ArticleBMC plant biology2023

Weighted gene coexpression correlation network analysis reveals the potential molecular regulatory mechanism of citrate and anthocyanin accumulation between postharvest 'Bingtangcheng' and 'Tarocco' blood orange fruit.

Yan Jin, Manyu Liao, Na Li, Xiaoqian Ma, Huimin Zhang, Jian Han, Dazhi Li, Junfeng Yang, Xiaopeng Lu, Guiyou Long and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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  5. Molecular Functional and Transcriptome Analysis ofPlants (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yan Jin *National Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Manyu Liao *National Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Na LiNational Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Xiaoqian MaNational Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Huimin ZhangNational Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Jian HanHunan Horticultural Research Institute, Changsha, CS, China.
Dazhi LiNational Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Junfeng YangNational Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Xiaopeng LuNational Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Guiyou LongNational Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Ziniu DengNational Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China.
Ling ShengNational Center for Citrus Improvement Changsha, College of Horticulture, Hunan Agricultural University, Changsha, CS, China. shengling0629@163.com.
Hunan Agricultural University · CNHunan Rice Research Institute · CN

Funding

General Fund Project of Hunan Natural Science Foundation 2022JJ30292Scientific Research Project of Education Department of Hunan Province 20A251the Natural Science Foundation of China 31801914
6 · The paper itself

Abstract

backgroundOrganic acids and anthocyanins are the most important compounds for the flavor and nutritional quality of citrus fruit. However, there are few reports on the involvement of co-regulation of citrate and anthocyanin metabolism. Here, we performed a comparative transcriptome analysis to elucidate the genes and pathways involved in both citrate and anthocyanin accumulation in postharvest citrus fruit with 'Tarocco' blood orange (TBO; high accumulation) and 'Bingtangcheng' sweet orange (BTSO; low accumulation).

resultsA robust core set of 825 DEGs were found to be temporally associated with citrate and anthocyanin accumulation throughout the storage period through transcriptome analysis. Further according to the results of weighted gene coexpression correlation network analysis (WGCNA), the turquoise and brown module was highly positively correlated with both of the content of citrate and anthocyanin, and p-type ATPase (PH8), phosphoenolpyruvate carboxylase kinase (PEPCK), chalcone isomerase (CHI), flavanone 3-hydroxylase (F3H), flavonoid 3'-hydroxylase (F3'H) and glutathione S transferase (GST) were considered key structural genes. Moreover, MYB family transcription factor (PH4), Zinc finger PHD-type transcription factor (CHR4, HAC12), Zinc finger SWIM-type transcription factor (FAR1) and Zinc finger C3H1-type transcription factor (ATC3H64) were considered hub genes related to these structural genes. Further qRT-PCR analysis verified that these transcription factors were highly expressed in TBO fruit and their expression profiles were significantly positively correlated with the structural genes of citrate and anthocyanin metabolism as well as the content of citrate and anthocyanin content.

conclusionsThe findings suggest that the CHR4, FAR1, ATC3H64 and HAC12 may be the new transcription regulators participate in controlling the level of citrate and anthocyanin in postharvest TBO fruit in addition to PH4. These results may providing new insight into the regulation mechanism of citrate and anthocyanin accumulation in citrus fruit.

Indexed as

AnthocyaninsCitrus sinensisCitric AcidFruitGene Expression Regulation, PlantPlant ProteinsTranscription FactorsTranscriptomeAnthocyaninsCitric AcidPlant ProteinsTranscription FactorsAnthocyanin‘Bingtangcheng’ sweet orangeCitratePostharvest‘Tarocco’ blood orangeTranscriptome

Identifiers

PMID37268922
PMCPMC10236656
OpenAlexW4379185325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.