Evidence map›Paper›PMID 37268843›Full record

Trial reportClinical oral investigations2023

Cryotherapy and pain intensity during endodontic treatment of mandibular first permanent molars with symptomatic irreversible pulpitis: A randomized controlled trial.

Ahmad Abdel Hamid Elheeny, Dania Ibrahem Sermani, Esteer Azer Saliab, Mohammed Turky

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05267847 (The Success Rate of Cryotherapy Application in Primary Molars With Signs of Irreversible), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05267847 naunknown statusnot on this map

The Success Rate of Cryotherapy Application in Primary Molars With Signs of Irreversible

TypeinterventionalSponsorMinia UniversityRan2022 to 2022Enrolled188ConditionsPain, ProceduralArmsCryotherapy, Traditional local anesthesia
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ahmad Abdel Hamid ElheenyPaediatric and Community Dentistry, Faculty of Dentistry, Minia University, Minya, Egypt. ahmedelheeny@mu.edu.eg.
Dania Ibrahem SermaniMinia University Dental Hospital, Faculty of Dentistry Hospital of Minia University, Minya, Egypt.
Esteer Azer SaliabPaediatric and Community Dentistry, Faculty of Dentistry, Minia University, Minya, Egypt.
Mohammed TurkyFaculty of Dentistry, Minia University, Minya, Egypt.
Minia University · EGMinia University Hospital · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe study aimed to assess the effectiveness of cryotherapy application after inferior alveolar nerve block (IANB) administration of the mandibular first permanent molars with symptomatic irreversible pulpitis (SIP) in adolescence. The secondary outcome was to compare the need for supplemental intraligamentary injection (ILI). MATERIALS AND

methodsThe study was designed as a randomized clinical trial including 152 participants aged from 10 to 17 years who were randomly assigned to two equal groups; cryotherapy plus IANB (intervention group) and the control group (conventional INAB). Both groups received 3.6 mL of 4% articaine. For the intervention group, ice packs were applied in the buccal vestibule of the mandibular first permanent molar for 5 min. Endodontic procedures started after 20 min for efficiently anesthetized teeth. The intraoperative pain intensity was measured using the visual analogue scale (VAS). The Mann-Whitney (U) and chi-square tests were applied to analyze data. The significance level was set to 0.05.

resultsThere was a significant reduction in the overall intraoperative VAS mean in the cryotherapy group compared to that in the control group (p = 0.004). The success rate was significantly higher in the cryotherapy group (59.2%) compared to the control group (40.8%). The frequency of extra ILI was 50% and 67.1% in the cryotherapy and control groups, respectively (p = 0.032).

conclusionsThe cryotherapy application boosted the efficacy of pulpal anesthesia of the mandibular first permanent molars with SIP in patients below the age of 18 years. Additional anesthesia was still necessary for optimal control over pain. CLINICAL RELEVANCE: Pain control during endodontic treatment of primary molars with irreversible pulpitis (IP) is a significant factor in a child's behavior in the dental office. Although the inferior alveolar nerve block (IANB) is the most commonly used technique to anaesthetize mandibular dentition, we found its success rate to be relatively low during endodontic treatment of primary molars with IP. Cryotherapy is a new approach that significantly improves the efficacy of IANB. CLINICAL

trial registrationThe trial was registered at ClinicalTrials.gov (reference no. NCT05267847).

Indexed as

Anesthesia, DentalNerve BlockPulpitisAdolescentAnesthetics, LocalChildCryotherapyDouble-Blind MethodHumansLidocaineMandibular NerveMolarPainPain MeasurementAnesthetics, LocalLidocaineCryotherapyPainSymptomatic irreversible pulpitis

Identifiers

PMID37268843
PMCPMC10415469
OpenAlexW4379197508

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.