Evidence map›Paper›PMID 37268035›Full record

ArticleThe Journal of pediatrics2023

Congenital Heart Disease with Congenital Diaphragmatic Hernia: Surgical Decision Making and Outcomes.

Latoya A Stewart, Rebecca R Hernan, Christopher Mardy, Eunice Hahn, Wendy K Chung, Emile A Bacha, Ganga Krishnamurthy, Vincent P Duron, Usha S Krishnan

Open access · greenAbstract read
In one paragraph

Article in The Journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Congenital heart disease and congenital diaphragmatic hernia: the role of intracardiac shunts.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  4. A hemodynamic-driven approach to chronic pulmonary hypertension in congenital diaphragmatic hernia.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  5. Article
  6. Hemodynamic precision to guide surgical timing for neonates with congenital diaphragmatic hernia: a narrative review.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Latoya A StewartColumbia University Vagelos College of Physicians and Surgeons, New York, NY.
Rebecca R HernanDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY.
Christopher MardyDivision of Pediatric Cardiology, Columbia University Irving Medical Center, New York, NY.
Eunice HahnDivision of Pediatric Cardiology, Columbia University Irving Medical Center, New York, NY.
Wendy K ChungDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY.
Emile A BachaDivision of Cardiothoracic Surgery, Columbia University Irving Medical Center, New York, NY.
Ganga KrishnamurthyDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY.
Vincent P DuronDivision of Pediatric Surgery, Columbia University Irving Medical Center, New York, NY.
Usha S KrishnanDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY; Division of Pediatric Cardiology, Columbia University Irving Medical Center, New York, NY. Electronic address: usk1@cumc.columbia.edu.
Columbia University Irving Medical Center · USColumbia University · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024156 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2006 to 2011
$53.0M
THE DROSOPHILA GENETICS AND RNAI CORE (THE FLY CORE)P01HD068250 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI CHUNG, WENDY K, DONAHOE, PATRICIA K · 2011 to 2022
$17.1M
Identification of Novel Genes for Congenital Diaphragmatic HerniaR01HD057036 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ASPELUND, GUDRUN, CHUNG, WENDY K · 2008 to 2012
$2.8M
NCRR NIH HHS UL1 RR024156NICHD NIH HHS P01 HD068250NICHD NIH HHS R01 HD057036
6 · The paper itself

Abstract

objectiveTo describe the types of congenital heart disease (CHD) in a congenital diaphragmatic hernia (CDH) cohort in a large volume center and evaluate surgical decision making and outcomes based on complexity of CHD and associated conditions. STUDY

designA retrospective review of patients with CHD and CDH diagnosed by echocardiogram between 01/01/2005 and 07/31/2021. The cohort was divided into 2 groups based on survival at discharge.

resultsClinically important CHD was diagnosed in 19% (62/326) of CDH patients. There was 90% (18/20) survival in children undergoing surgery for both CHD and CDH as neonates, and 87.5 (22/24) in those undergoing repair initially for CDH alone. A genetic anomaly identified on clinical testing was noted in 16% with no significant association with survival. A higher frequency of other organ system anomalies was noted in nonsurvivors compared with survivors. Nonsurvivors were more likely to have unrepaired CDH (69% vs 0%, P < .001) and unrepaired CHD (88% vs 54%, P < .05), reflecting a decision not to offer surgery.

conclusionsSurvival was excellent in patients who underwent repair of both CHD and CDH. Patients with univentricular physiology have poor survival and this finding should be incorporated into pre and postnatal counseling about eligibility for surgery. In contrast, patients with other complex lesions including transposition of the great arteries have excellent outcomes and survival at 5 years follow-up at a large pediatric and cardiothoracic surgical center.

Indexed as

Heart Defects, CongenitalHernias, Diaphragmatic, CongenitalTransposition of Great VesselsChildDecision MakingHumansInfant, NewbornRetrospective StudiesSurvival Ratecardiac and thoracic surgerygeneticsoutcomesprenatal counseling

Identifiers

PMID37268035
PMCPMC10527207
OpenAlexW4378840063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.