Evidence map›Paper›PMID 37267631›Full record

ArticleJournal of medicinal chemistry2023

Structure-Activity Relationship Studies of the Aryl Acetamide Triazolopyridazines against

Tanner J Schubert, Edmund Oboh, Hannah Peek, Emily Philo, José E Teixeira, Erin E Stebbins, Peter Miller, Jonathan Oliva, Francis M Sverdrup, David W Griggs and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Discovery of an Orally Efficacious Pyrazolo[3,4-Journal of medicinal chemistry · 2025
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Tanner J SchubertDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
Edmund ObohDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
Hannah PeekDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
Emily PhiloDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
José E TeixeiraDepartment of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont 05401, United States.
Erin E StebbinsDepartment of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont 05401, United States.
Peter MillerDepartment of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont 05401, United States.
Jonathan OlivaDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, Missouri 63104, United States.
Francis M SverdrupDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, Missouri 63104, United States.
David W GriggsInstitute for Drug and Biotherapeutic Innovation, Saint Louis University, St. Louis, Missouri 63103, United States.
Christopher D HustonDepartment of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont 05401, United States.
Marvin J MeyersDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.ORCID 0000-0001-5484-619X
Saint Louis University · USUniversity of Vermont · US

Funding

Preclinical optimization of a parasiticidal drug for cryptosporidiosisR01AI143951 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HUSTON, CHRISTOPHER D, MEYERS, MARVIN J · 2019 to 2023
$3.3M
NIAID NIH HHS R01 AI143951
6 · The paper itself

Abstract

Our previous work identified compound

Indexed as

CryptosporidiosisCryptosporidiumAnimalsFluorineMiceStructure-Activity RelationshipFluorine

Identifiers

PMID37267631
PMCPMC11103792
OpenAlexW4379114961

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.