Evidence map›Paper›PMID 37267401›Full record

Observational studyPloS one2023

ABO blood group as a determinant of COVID-19 and Long COVID: An observational, longitudinal, large study.

Joan B Soriano, Adrián Peláez, Xavier Busquets, María Rodrigo-García, Elena Ávalos Pérez-Urría, Tamara Alonso, Rosa Girón, Claudia Valenzuela, Celeste Marcos, Elena García-Castillo and 1 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Joan B SorianoServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.ORCID 0000-0001-9740-2994
Adrián PeláezServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.
Xavier BusquetsLaboratory of Molecular Cell Biomedicine, University of the Balearic Islands, Palma, Spain.
María Rodrigo-GarcíaServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.
Elena Ávalos Pérez-UrríaServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.ORCID 0000-0002-9988-4605
Tamara AlonsoServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.
Rosa GirónServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.
Claudia ValenzuelaServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.
Celeste MarcosServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.
Elena García-CastilloServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.ORCID 0000-0002-4190-6533
Julio AncocheaServicio de Neumología, Hospital Universitario de la Princesa, Madrid, Spain.ORCID 0000-0003-0284-6643
Hospital Universitario de La Princesa · ESInstituto de Salud Carlos III · ESUniversitat de les Illes Balears · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn association of ABO blood group and COVID-19 remains controversial.

methodsFollowing STROBE guidance for observational research, we explored the distribution of ABO blood group in patients hospitalized for acute COVID-19 and in those with Long COVID. Contingency tables were made and risk factors were explored using crude and adjusted Mantle-Haentzel odds ratios (OR and 95% CI).

resultsUp to September 2022, there were a total of 5,832 acute COVID-19 hospitalizations in our hospital, corresponding to 5,503 individual patients, of whom blood group determination was available for 1,513 (27.5%). Their distribution by ABO was: 653 (43.2%) group 0, 690 (45.6%) A, 113 (7.5%) B, and 57 (3.8%) AB, which corresponds to the expected frequencies in the general population. In parallel, of 676 patients with Long COVID, blood group determination was available for 135 (20.0%). Their distribution was: 60 (44.4%) from group 0, 61 (45.2%) A, 9 (6.7%) B, and 5 (3.7%) AB. The distribution of the ABO system of Long COVID patients did not show significant differences with respect to that of the total group (p ≥ 0.843). In a multivariate analysis adjusting for age, sex, ethnicity, and severity of acute COVID-19 infection, subgroups A, AB, and B were not significantly associated with developing Long COVID with an OR of 1.015 [0.669-1.541], 1.327 [0.490-3.594] and 0.965 [0.453-2.058], respectively. The effect of the Rh+ factor was also not significant 1,423 [0.772-2,622] regarding Long COVID.

conclusionsNo association of any ABO blood subgroup with COVID-19 or developing Long COVID was identified.

Indexed as

COVID-19ABO Blood-Group SystemHumansLongitudinal StudiesPost-Acute COVID-19 SyndromeRh-Hr Blood-Group SystemRisk FactorsABO Blood-Group SystemRh-Hr Blood-Group System

Identifiers

PMID37267401
PMCPMC10237493
OpenAlexW4379184808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.