Evidence map›Paper›PMID 37267383›Full record

ArticleScience immunology2023

Chronic antigen in solid tumors drives a distinct program of T cell residence.

Noah V Gavil, Milcah C Scott, Eyob Weyu, Olivia C Smith, Stephen D O'Flanagan, Sathi Wijeyesinghe, Sahar Lotfi-Emran, Stephen L Shiao, Vaiva Vezys, David Masopust

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Decoding T cell exhaustion in the tumour microenvironment.Experimental & molecular medicine · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Oral immunization withJournal for immunotherapy of cancer · 2026
    Article
  8. Article
  9. Article
  10. Tumor-driven stabilization of CD8Frontiers in immunology · 2026
    Review
  11. Article
  12. Review
  13. The diversity of CD8Nature reviews. Immunology · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Differentiation of Cytotoxic CD8Cancer science · 2025
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Noah V GavilDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0003-4686-4181
Milcah C ScottDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0003-2151-7335
Eyob WeyuDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0002-1755-0354
Olivia C SmithDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0002-2788-9917
Stephen D O'FlanaganDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0002-9286-1208
Sathi WijeyesingheDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0002-8819-2654
Sahar Lotfi-EmranDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0002-8650-6779
Stephen L ShiaoDepartment of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0001-7586-2885
Vaiva VezysDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0002-2520-809X
David MasopustDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0002-9440-3884
University of Minnesota Medical Center · USCedars-Sinai Medical Center · US

Funding

Mucosal T Cell Memory to PathogensR01AI084913 · NIAID · UNIVERSITY OF MINNESOTA · PI MASOPUST, DAVID · 2010 to 2023
$5.8M
Resident Memory T CellsR01AI146032 · NIAID · UNIVERSITY OF MINNESOTA · PI DAVID MASOPUST · 2020 to 2026
$3.8M
Repurposing TRM for tumor immunotherapyR01CA238439 · NCI · UNIVERSITY OF MINNESOTA · PI MASOPUST, DAVID · 2020 to 2024
$2.5M
New mouse model to better predict human immunity to influenza vaccination and infectionR01AI150600 · NIAID · UNIVERSITY OF MINNESOTA · PI LANGLOIS, RYAN, MASOPUST, DAVID · 2021 to 2024
$2.5M
Investigating mechanisms of peptide alarm therapyF30CA253992 · NCI · UNIVERSITY OF MINNESOTA · PI GAVIL, NOAH VEIS · 2020 to 2023
$167k
Defining tissue specific phenotypes that faithfully identify tissue resident memory T cellsF31AI152353 · NIAID · UNIVERSITY OF MINNESOTA · PI SCOTT, MILCAH C · 2021 to 2022
$65k
NCI NIH HHS F30 CA253992NCI NIH HHS R01 CA238439NIAID NIH HHS F31 AI152353NIAID NIH HHS R01 AI084913NIAID NIH HHS R01 AI146032NIAID NIH HHS R01 AI150600
6 · The paper itself

Abstract

Analyses of healthy tissue reveal signatures that identify resident memory CD8

Indexed as

CD8-Positive T-LymphocytesNeoplasmsAnimalsAntigensImmunologic MemoryMicePrognosisTumor MicroenvironmentAntigens

Identifiers

PMID37267383
PMCPMC10569081
OpenAlexW4379136375

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.