ArticleScience advances2023
Pneumatic computers for embedded control of microfluidics.
Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- A bio-inspired customizable mechanical central pattern generator enables one-to-many scalable pneumatic control.Communications engineering · 2026Article
- Recent Advances in MEMS Actuators for Microfluidic Applications: Emerging Designs, Multiphysics Modeling, and Performance Optimization.Micromachines · 2026Review
- Rotary Electromechanical System Integrating Non-Reciprocal Memory and Combinational Logic.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A kinematically Bifurcated Metamaterial for Integrated Logic Operation and Computing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Improving engineered biological systems with electronics and microfluidics.Nature biotechnology · 2025Review
- Controlling Biomedical Devices Using Pneumatic Logic.Annals of biomedical engineering · 2025Article
- Pneumatic coding blocks enable programmability of electronics-free fluidic soft robots.Science advances · 2024Article
- Mechanical Neural Networks with Explicit and Robust Neurons.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Intelligent electroactive material systems with self-adaptive mechanical memory and sequential logic.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Alternative computing approaches that interface readily with physical systems are well suited for embedded control of those systems. We demonstrate finite state machines implemented as pneumatic circuits of microfluidic valves and use these controllers to direct microfluidic liquid handling procedures on the same chip. These monolithic integrated systems require only power to be supplied externally, in the form of a vacuum source. User input can be provided directly to the chip by covering pneumatic ports with a finger. State machines with up to four bits of state memory are demonstrated, and next-state combinational logic can be fully reprogrammed by changing the hole-punch pattern on a membrane in the chip. These pneumatic computers demonstrate a framework for the embedded control of physical systems and open a path to stand-alone lab-on-a-chip devices capable of highly complex functionality.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.