Evidence map›Paper›PMID 37267226›Full record

ArticleG3 (Bethesda, Md.)2023

A resource of human coronavirus protein-coding sequences in a flexible, multipurpose Gateway Entry clone collection.

Benjamin Weller, Chung-Wen Lin, Oxana Pogoutse, Mayra Sauer, Nora Marin-de la Rosa, Alexandra Strobel, Veronika Young, Jennifer J Knapp, Ashyad Rayhan, Claudia Falter and 3 more

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Benjamin WellerInstitute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Munich-Neuherberg, Germany.
Chung-Wen LinInstitute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Munich-Neuherberg, Germany.
Oxana PogoutseDonnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, 160 College St, Toronto, Ontario M5S 3E1, Canada.
Mayra SauerInstitute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Munich-Neuherberg, Germany.
Nora Marin-de la RosaInstitute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Munich-Neuherberg, Germany.
Alexandra StrobelInstitute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Munich-Neuherberg, Germany.
Veronika YoungInstitute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Munich-Neuherberg, Germany.
Jennifer J KnappDonnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, 160 College St, Toronto, Ontario M5S 3E1, Canada.
Ashyad RayhanDonnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, 160 College St, Toronto, Ontario M5S 3E1, Canada.
Claudia FalterInstitute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Munich-Neuherberg, Germany.
Dae-Kyum KimDonnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, 160 College St, Toronto, Ontario M5S 3E1, Canada.
Frederick P RothDonnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, 160 College St, Toronto, Ontario M5S 3E1, Canada.
Pascal Falter-BraunInstitute of Network Biology (INET), Molecular Targets and Therapeutics Center (MTTC), Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Munich-Neuherberg, Germany.
Helmholtz Zentrum München · DEDana-Farber Cancer Institute · USUniversity of Toronto · CAUniversity of New Brunswick · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has catalyzed unprecedented scientific data and reagent sharing and collaboration, which enabled understanding the virology of the SARS-CoV-2 virus and vaccine development at record speed. The pandemic, however, has also raised awareness of the danger posed by the family of coronaviruses, of which 7 are known to infect humans and dozens have been identified in reservoir species, such as bats, rodents, or livestock. To facilitate understanding the commonalities and specifics of coronavirus infections and aspects of viral biology that determine their level of lethality to the human host, we have generated a collection of freely available clones encoding nearly all human coronavirus proteins known to date. We hope that this flexible, Gateway-compatible vector collection will encourage further research into the interactions of coronaviruses with their human host, to increase preparedness for future zoonotic viral outbreaks.

Indexed as

COVID-19HumansPandemicsSARS-CoV-2229Ecoding sequencecoronavirusGateway Entry cloneHCoVHKU1MERSNL63OC43SARS-CoV-2

Identifiers

PMID37267226
PMCPMC10320145
OpenAlexW4379197668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.