Evidence map›Paper›PMID 37267178›Full record

ArticleJournal of addiction medicine

Defining Prescription Drug Misuse: A Naturalistic Evaluation of National Survey on Drug Use and Health Data From 2012-2014 to 2015-2017.

R Kathryn McHugh, Victoria R Votaw, Megan D McCarthy, Juliette A Bichon, Allen J Bailey, Garrett M Fitzmaurice

Abstract read
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Internet Gaming Disorder and Nonmedical Prescription Drug Use: The Moderating Role of Student Status.International journal of environmental research and public health · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

R Kathryn McHughFrom the McLean Hospital, Belmont, MA (RKM, MDM, JAB, AJB, GMF); Harvard Medical School, Boston, MA (RKM, AJB, GMF); and University of New Mexico, Albuquerque, NM (VRV).
Victoria R Votaw
Megan D McCarthy
Juliette A Bichon
Allen J Bailey
Garrett M Fitzmaurice

Funding

Affective and Inflammatory Reactivity to Pain in Opioid Use DisorderR01DA045632 · NIDA · MCLEAN HOSPITAL · PI MCHUGH, REBECCA KATHRYN · 2019 to 2022
$1.5M
Reduction in frequency of drug use as a primary outcome and its relation to changes in health-related and other functional outcomes in stimulant use disorder trialsR33DA042847 · NIDA · MCLEAN HOSPITAL · PI FITZMAURICE, GARRETT M · 2019 to 2021
$1.3M
Validating Reward and Relief Drinking Phenotypes: A Multimethod AssessmentF31AA029266 · NIAAA · UNIVERSITY OF NEW MEXICO · PI VOTAW, VICTORIA · 2021 to 2022
$77k
NIAAA NIH HHS F31 AA029266NIDA NIH HHS R01 DA045632NIDA NIH HHS R33 DA042847
6 · The paper itself

Abstract

objectivesPrescription drug misuse (PDM) is a significant public health problem. As research has evolved, the definitions of misuse have varied over time, yet the implications of this variability have not been systematically studied. The objective of this study was to leverage a change in the measurement of PDM in a large population survey to identify its impact on the prevalence and correlates of this behavior.

methodsData from the National Survey on Drug Use and Health were compared before and after a change in the definition of PDM from one that restricted the source and motive for use to one that captured any misuse other than directed by a prescriber. Three-year cohorts were constructed, representing a restricted definition of PDM (2012-2014) and a broad definition of PDM (2015-2017).

resultsSegmented logistic regression models indicated a significant increase in PDM prevalence for all 3 drug types examined (opioids, tranquilizers, and sedatives). Although the magnitude of differences varied somewhat based on drug type, the broader definition was generally associated with older age, higher prevalence of health insurance, and higher odds of misusing one's own prescription. Some worsening of mental health indicators was observed, but results indicated few other clinical or substance use differences.

conclusionsDefinitions of prescription drug misuse have a substantial impact on the prevalence of misuse and some impact on the characteristics of the population. Further research is needed to understand the optimal strategy for measuring this behavior, based on the scientific or public health question or interest.

Indexed as

Prescription Drug MisuseSubstance-Related DisordersTranquilizing AgentsAnalgesics, OpioidHumansHypnotics and SedativesAnalgesics, OpioidHypnotics and SedativesTranquilizing Agents

Identifiers

PMID37267178
PMCPMC10248189

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.