Evidence map›Paper›PMID 37266880›Full record

ArticleBiotechnology letters2023

Improved membrane stability of alginate-chitosan microcapsules by crosslinking with tannic acid.

Li Chen, Fang Jiang, Haidan Xu, Yaoyao Fan, Cunbin Du

Abstract read
PubMed Publisher
In one paragraph

Article in Biotechnology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Li ChenCollege of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, Zhejiang, People's Republic of China. chenl01@tzc.edu.cn.ORCID http://orcid.org/0000-0002-3663-2267
Fang JiangSchool of Pharmaceutical and Chemical Engineering, Taizhou University, No. 1139, Shifu Avenue, Jiaojiang District, Taizhou, 318000, Zhejiang, People's Republic of China.
Haidan XuSchool of Pharmaceutical and Chemical Engineering, Taizhou University, No. 1139, Shifu Avenue, Jiaojiang District, Taizhou, 318000, Zhejiang, People's Republic of China.
Yaoyao FanSchool of Pharmaceutical and Chemical Engineering, Taizhou University, No. 1139, Shifu Avenue, Jiaojiang District, Taizhou, 318000, Zhejiang, People's Republic of China.
Cunbin DuSchool of Pharmaceutical and Chemical Engineering, Taizhou University, No. 1139, Shifu Avenue, Jiaojiang District, Taizhou, 318000, Zhejiang, People's Republic of China.

Funding

Science and Technology Plan Project of Taizhou 2003gy16
6 · The paper itself

Abstract

objectiveThe insufficient stability of alginate-chitosan (ALG-CS) microcapsules in biorelevant media limits their applications in the biomedical field. Attempts were made to improve the membrane stability of ALG-CS microcapsules by noncovalent crosslinking with tannic acid.

resultsThe membrane stability of ALG-CS microcapsules in culture medium and serum was significantly improved by crosslinking with tannic acid. Moreover, the reason for the significant improvement in membrane stability had been demonstrated to be that the stability of chitosan-tannic acid (CS-TA) polyelectrolyte complexes was less affected by the competitive binding of those weak acid ions such as HCO

conclusionThe study provides a novel approach for improving the stability of the ALG-CS microcapsules in biorelevant media to expand their scope of application in the biological field.

Indexed as

ChitosanAlginatesCapsulesPolyphenolsAlginatesCapsulesChitosanPolyphenolstannic acidAlginateChitosanMechanical stabilityMicrocapsuleTannic acid

Identifiers

PMID37266880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.