Evidence map›Paper›PMID 37266700›Full record

ArticleMikrochimica acta2023

Highly sensitive and specific resonance Rayleigh scattering detection of esophageal cancer cells via dual-aptamer target binding strategy.

Junbo Li, Jinghua Wang, Dandan Ma, Huiyun Bai

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Junbo LiPharmaceutical Department, Changzhi Medical College, Changzhi, 046000, China. lijunbo81@163.com.ORCID http://orcid.org/0000-0001-8794-8491
Jinghua WangDepartment of Traditional Chinese Medicine, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, ,046000, China.
Dandan MaPharmaceutical Department, Changzhi Medical College, Changzhi, 046000, China.
Huiyun BaiPharmaceutical Department, Changzhi Medical College, Changzhi, 046000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The modification of EGFR aptamer (Apt 1) and HER2 aptamer (Apt 2) with gold nanoparticles (AuNPs) is reported to obtain probe I (Apt 1-AuNPs) and probe II (Apt 2-AuNPs). Taking Eca109, KYSE510, and KYSE150 cells as models, the sandwich scattering system of probe I-cell-probe II was formed by the recognition of tumor markers by the aptamer modified probe, and the resonance Rayleigh scattering (RRS) spectra were investigated. The results showed that the scattering system can be used to quantitatively detect the Eca109 cell lines in the range 5.0×10 to 5.0×10

Indexed as

Aptamers, NucleotideEsophageal NeoplasmsMetal NanoparticlesGoldHumansAptamers, NucleotideGoldAu nanoparticlesCancer cellDual-probeEsophageal squamous cell carcinomaResonance Rayleigh scattering

Identifiers

PMID37266700

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.