Evidence map›Paper›PMID 37266687›Full record

ArticleAnalytical and bioanalytical chemistry2023

Rapid detection of carbamate nerve agent analogues using dually functionalized gold nanoclusters.

Qiaoli Zhang, Jiale Lv, Junmei Xia, Liangliang Wang, Gang Qu, Yuntao Yang, Yang Yang, Shilei Liu

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In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qiaoli ZhangState Key Laboratory of NBC Protection for Civilian, Beijing, 102205, China.
Jiale LvCollege of Chemical Engineering, Sichuan University of Science and Engineering, Zigong, 643000, China.
Junmei XiaState Key Laboratory of NBC Protection for Civilian, Beijing, 102205, China.
Liangliang WangState Key Laboratory of NBC Protection for Civilian, Beijing, 102205, China.
Gang QuCollege of Chemical Engineering, Sichuan University of Science and Engineering, Zigong, 643000, China.
Yuntao YangState Key Laboratory of NBC Protection for Civilian, Beijing, 102205, China.
Yang YangState Key Laboratory of NBC Protection for Civilian, Beijing, 102205, China. ricdyihui@163.com.
Shilei LiuState Key Laboratory of NBC Protection for Civilian, Beijing, 102205, China. liu_shilei@lacricd.com.

Funding

The work was supported by the State Key Laboratory of NBC Protection for Civilian SKLNBC 2020-17
6 · The paper itself

Abstract

Carbamate nerve agents (CMNAs) are a type of lethal cholinesterase inhibitor with one or more quaternary amine centres and aromatic rings. CMNAs have been recently added to the Annex on Chemicals of the Chemical Weapons Convention (CWC) and Schedules of Controlled Chemicals of China. In this study, a rapid, sensitive and selective method was developed for the fluorescence detection of ambenonium chloride (AC) through host-guest and electrostatic dual interactions between AC and cyclodextrin/11-mercaptoundecanoic acid (CD/MUA) dually functionalized gold nanoclusters (AuNCs). Through this method, AC was detected with a limit of detection of 10.0 ng/mL. Method evaluation showed high selectivity towards AC over other related compounds. The practical applicability was verified, as satisfactory recoveries were obtained for AC spiked in river water and urine, as well as Proficiency Test samples from Organisation for the Prohibition of Chemical Weapons (OPCW). In addition, a fluorescence sensing array comprising four AuNCs was designed to distinguish six carbamates and structurally similar compounds. This method provides a potential approach for the rapid, sensitive and selective recognition and detection of CMNAs.

Indexed as

Metal NanoparticlesNerve AgentsCarbamatesChinaGoldLimit of DetectionSpectrometry, FluorescenceCarbamatesGoldNerve AgentsAmbenonium chlorideCarbamate nerve agentsDually functionalized gold nanoclustersFluorescence sensing arrayRapid detection

Identifiers

PMID37266687

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.