Evidence map›Paper›PMID 37266578›Full record

ArticleeLife2023

Defining function of wild-type and three patient-specific

Jiangfei Chen, Kunal Baxi, Amanda E Lipsitt, Nicole Rae Hensch, Long Wang, Prethish Sreenivas, Paulomi Modi, Xiang Ru Zhao, Antoine Baudin, Daniel G Robledo and 12 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Choosing the right animal model for sarcoma research.Cellular and molecular life sciences : CMLS · 2026
    Review
  2. Striated muscle: an inadequate soil for cancers.Cancer metastasis reviews · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 3 countries.

Jiangfei Chen *Institute of Environmental Safety and Human Health, Wenzhou Medical University, Wenzhou, China.
Kunal Baxi *Greehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Amanda E LipsittGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.ORCID 0000-0002-3757-8493
Nicole Rae HenschGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.ORCID 0000-0001-9946-0995
Long WangGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.ORCID 0000-0002-7935-4148
Prethish SreenivasGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Paulomi ModiGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Xiang Ru ZhaoGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Antoine BaudinGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Daniel G RobledoGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Abhik BandyopadhyayGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Aaron SugalskiDepartment of Pediatrics, Division of Hematology Oncology, UT Health Sciences Center, San Antonio, United States.
Anil K ChallaGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Dias KurmashevGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Andrea R GilbertDepartment of Pathology and Laboratory Medicine, UT Health Sciences Center, San Antonio, United States.
Gail E TomlinsonGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Peter HoughtonGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.
Yidong ChenDepartment of Population Health Sciences, UT Health Sciences Center, San Antonio, United States.
Madeline N HayesDevelopmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Canada.
Eleanor Y ChenDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, United States.
David S LibichGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.ORCID 0000-0001-6492-2803
Myron S IgnatiusGreehey Children's Cancer Research Institute (GCCRI), UT Health Sciences Center, San Antonio, United States.ORCID 0000-0001-6639-7707
Children's Cancer Center · USThe University of Texas Health Science Center at Houston · USCancer Research Institute · USHospital for Sick Children · CAUniversity of Alabama at Birmingham · USUniversity of Washington · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Cancer Biology Training ProgramT32CA148724 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Pei Wang, Feng-Chun Yang · 2011 to 2026
$3.3M
NRSA Training Core (TL1)TL1TR002647 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHUN, YONG-HEE PATRICIA, FREI, CHRISTOPHER R. · 2018 to 2022
$1.8M
A role for notch in self renewal in embryonal rhabdomyosarcomaR00CA175184 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI IGNATIUS, MYRON STEVE · 2017 to 2019
$747k
Illumina NovaSeq 6000 Sequencing SystemS10OD030311 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2021 to 2021
$600k
NCATS NIH HHS TL1 TR002647NCI NIH HHS P30 CA054174NCI NIH HHS R00 CA175184NCI NIH HHS T32 CA148724NIH HHS R00CA1715184NIH HHS R00CA175184NIH HHS S10 OD030311
6 · The paper itself

Abstract

In embryonal rhabdomyosarcoma (ERMS) and generally in sarcomas, the role of wild-type and loss- or gain-of-function

Indexed as

Cerebellar NeoplasmsRhabdomyosarcoma, EmbryonalAnimalsCarcinogenesisMutationProto-Oncogene Proteins p21(ras)Tumor Suppressor Protein p53ZebrafishZebrafish ProteinsProto-Oncogene Proteins p21(ras)tp53 protein, zebrafishTumor Suppressor Protein p53Zebrafish Proteinscancer biologymutant tp53rare varientsrhabdomyosarcomaTP53TP53C176FTP53P153ΔTP53Y220Ctumor initiationzebrafish

Identifiers

PMID37266578
PMCPMC10322150
OpenAlexW4379095348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.