Evidence map›Paper›PMID 37266566›Full record

ArticleeLife2023

Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to

Sharon A McGrath-Morrow, Jarrett Venezia, Roland Ndeh, Nigel Michki, Javier Perez, Benjamin David Singer, Raffaello Cimbro, Mark Soloski, Alan L Scott

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sharon A McGrath-MorrowChildren's Hospital of Philadelphia Division of Pulmonary Medicine and Sleep, Philadelphia, United States.ORCID 0000-0002-1576-5394
Jarrett VeneziaW Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Baltimore, United States.ORCID 0000-0002-8736-0775
Roland NdehChildren's Hospital of Philadelphia Division of Pulmonary Medicine and Sleep, Philadelphia, United States.
Nigel MichkiChildren's Hospital of Philadelphia Division of Pulmonary Medicine and Sleep, Philadelphia, United States.
Javier PerezChildren's Hospital of Philadelphia Division of Pulmonary Medicine and Sleep, Philadelphia, United States.
Benjamin David SingerDivision of Pulmonary and Critical Care Medicine, Department of Medicine Northwestern, University Feinberg School of Medicine, Chicago, United States.ORCID 0000-0001-5775-8427
Raffaello CimbroDepartment of Medicine, Division of Rheumatology, Johns Hopkins University, School of Medicine, Baltimore, United States.
Mark SoloskiDepartment of Medicine, Division of Rheumatology, Johns Hopkins University, School of Medicine, Baltimore, United States.
Alan L ScottW Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Baltimore, United States.ORCID 0000-0003-0834-728X
Children's Hospital of Philadelphia · USJohns Hopkins University · US

Funding

Technology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JUSTIN B. STARREN · 2018 to 2026
$24.7M
The Cell Phenotyping and Mouse CoreP01HL154998 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2021 to 2026
$18.9M
Mechanisms of regulatory T cell-mediated recovery from severe viral pneumoniaR01HL149883 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Benjamin David Singer · 2020 to 2026
$4.1M
Resolution of Diffuse Inflammatory Lung Injury in Neonatal MiceR01HL114800 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MCGRATH-MORROW, SHARON ANN · 2013 to 2021
$3.3M
Mechanism of pathogenic macrophage activation in emphysemaR01HL140623 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MITZNER, WAYNE, SCOTT, ALAN L · 2018 to 2021
$2.4M
Epigenetic modifiers of regulatory T cell function following viral pneumoniaR01HL153122 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SINGER, BENJAMIN DAVID · 2021 to 2021
$63k
NHLBI NIH HHS P01 HL154998NHLBI NIH HHS R01 HL114800NHLBI NIH HHS R01 HL140623NHLBI NIH HHS R01 HL149883NHLBI NIH HHS R01 HL153122NIAID NIH HHS U19 AI135964
6 · The paper itself

Abstract

Bacterial pneumonia in neonates can cause significant morbidity and mortality when compared to other childhood age groups. To understand the immune mechanisms that underlie these age-related differences, we employed a mouse model of

Indexed as

Escherichia coli InfectionsPneumonia, BacterialAnimalsCytokinesEscherichia coliLungMiceMolecular Dynamics SimulationCytokinesE. coliimmunologyinfectious diseaseinflammationjuvenilelungsmacrophagemicrobiologymonocytemouseneonatalpneumonia

Identifiers

PMID37266566
PMCPMC10264069
OpenAlexW4379093378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.