ArticleJGH open : an open access journal of gastroenterology and hepatology2023
Prognostic significance of sarcopenia and severe vitamin D deficiency in patients with cirrhosis.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Correlation between sarcopenia and cirrhosis: a meta-analysis.Frontiers in nutrition · 2023Pooled it
- Radiological Assessment of Sarcopenia and Its Association with Metabolic Markers in Patients with Liver Cirrhosis.Journal of clinical medicine · 2026Article
- Low 25(OH)Vitamin D levels are associated with nutritional risk and disease severity in outpatient individuals with advanced chronic liver disease.Journal of nutritional science · 2026Article
- Prognostic associations of vitamin D deficiency with disease severity, survival, and complications in alcohol-related liver disease.Frontiers in medicine · 2026Article
- Nutritional Approach to Diabetic Sarcopenia: A Comprehensive Review.Current nutrition reports · 2025Review
- Efficacy of different nutrition interventions on sarcopenia in patients with cirrhosis: a systematic review and network meta-analysis.BMC nutrition · 2025Article
- Child-Pugh Score and Vitamin D: Exploring a New Frontier in Liver Cirrhosis Assessment.Cureus · 2024Article
- Effect of Vitamin D and Skeletal Muscle Mass on Prognosis of Patients with Diffuse Large B-Cell Lymphoma.Nutrients · 2024Article
- Association of chronic liver disease with bone diseases and muscle weakness.Journal of bone and mineral metabolism · 2024Review
- Vitamin D Deficiency Is Associated with Advanced Liver Fibrosis and Impaired Fasting Glucose in Alcohol Use Disorder.Nutrients · 2024Article
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Authors and funding
8 authors.
Funding
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Abstract
Background and Aim: Sarcopenia and severe vitamin D deficiency are associated with malnutrition and poor prognosis. We investigated the impact of the comorbidity of Child-Pugh (CP) class B/C cirrhosis and the aforementioned complications on the prognosis of patients with cirrhosis. Methods: We retrospectively evaluated 104 patients with cirrhosis. The cumulative survival rates were compared between patients with and without both or either of these disease conditions: CP class B/C and complications (sarcopenia or severe vitamin D deficiency). Sarcopenia was diagnosed according to the Japan Society of Hepatology criteria. Severe vitamin D deficiency was defined as levels of 25-hydroxyvitamin D <10 ng/mL in serum. Results: The prevalence of CP class B/C, sarcopenia, and severe vitamin D deficiency was 26.9%, 38.5%, and 24.0%, respectively. Patients with both CP class B/C and sarcopenia had significantly lower survival rates than those without both (hazard ratio [HR] = 6.101; Conclusions: The coexistence of CP class B/C and sarcopenia or severe vitamin D deficiency worsened the prognosis of patients with cirrhosis. Nutritional assessments such as sarcopenia and vitamin D status should be considered to better evaluate disease conditions and patient prognosis.
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