Evidence map›Paper›PMID 37265475›Full record

ArticleBioMed research international2023

Glutathione Upregulates the Expression of K

Ruslan Strutynskyi, Nataliіa Strutynska, Lidiia Mys, Yulia Goshovska, Yuliia Korkach, Raisa Fedichkina, Iryna Okhai, Vladyslav Strutynskyi, Vadym Sagach

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ruslan StrutynskyiDepartment of General and Molecular Pathophysiology, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4, Bogomoletz Str., Kyiv 01024, Ukraine.ORCID https://orcid.org/0000-0002-2189-7932
Nataliіa StrutynskaDepartment of Blood Circulation, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4, Bogomoletz Str., Kyiv 01024, Ukraine.
Lidiia MysDepartment of Blood Circulation, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4, Bogomoletz Str., Kyiv 01024, Ukraine.ORCID https://orcid.org/0000-0002-3943-4768
Yulia GoshovskaDepartment of Blood Circulation, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4, Bogomoletz Str., Kyiv 01024, Ukraine.
Yuliia KorkachDepartment of Blood Circulation, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4, Bogomoletz Str., Kyiv 01024, Ukraine.
Raisa FedichkinaDepartment of Blood Circulation, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4, Bogomoletz Str., Kyiv 01024, Ukraine.
Iryna OkhaiDepartment of Blood Circulation, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4, Bogomoletz Str., Kyiv 01024, Ukraine.
Vladyslav StrutynskyiDepartment of Immunophysiology, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4, Bogomoletz Str., Kyiv 01024, Ukraine.
Vadym SagachDepartment of Blood Circulation, Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4, Bogomoletz Str., Kyiv 01024, Ukraine.
National Academy of Sciences of Ukraine · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In the present work, we investigated the effect of exogenous glutathione in old rats on the expression of ATP-sensitive potassium (K Methods: Experiments were performed on adult (6 months) and old (24 months) male Wistar rats, which were divided into three groups: adult, old, and glutathione-treated old rats. Glutathione was injected intraperitoneally at a dose of 52 mg/kg 1 hour before the studies. The mRNA expression of K Results: It was shown that the expression levels of Kir6.1, Kir6.2, and SUR1 subunits of K Conclusions: Thus, the administration of exogenous glutathione to old rats resulted in a significant increase in the expression levels of the Kir6.1, Kir6.2, and SUR1 subunits of K

Indexed as

Mitochondria, HeartVasodilationAdenosine TriphosphateAnimalsMaleOxidative StressRatsRats, WistarAdenosine Triphosphate

Identifiers

PMID37265475
PMCPMC10232108
OpenAlexW4377965933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.