Evidence map›Paper›PMID 37265474›Full record

ArticleGeneral psychiatry2023

Baseline symptoms of depression and anxiety negatively impact the effectiveness of CBTi in treating acute insomnia among young adults.

Chenxi Zhang, Shufei Zeng, Yan Xu, Shuai Liu, Shixu Du, Leqin Fang, Zhihong Lv, Lili Zhang, Bin Zhang

Open access · diamondAbstract read
In one paragraph

Article in General psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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  7. Toward personalized care for insomnia in the US Army: a machine learning model to predict response to cognitive behavioral therapy for insomnia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Chenxi ZhangDepartment of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0001-8929-7506
Shufei ZengDepartment of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yan XuDepartment of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Shuai LiuDepartment of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Shixu DuDepartment of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Leqin FangDepartment of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhihong LvDepartment of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Lili ZhangDepartment of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Bin ZhangDepartment of Psychiatry, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0002-7016-0865
Nanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cognitive-behavioural therapy for insomnia (CBTi) is the first-line treatment for those with this sleep disorder. However, depressive and anxiety symptoms often co-occur with acute insomnia, which may affect the effectiveness of CBTi treatment. Aims: This study aimed to determine the impact of depressive and anxiety symptoms on the efficacy of CBTi in treating acute insomnia. Methods: A single-arm clinical trial was conducted among individuals who have acute insomnia. Participants underwent self-guided CBTi for 1-week. Their insomnia, depressive symptoms and anxiety symptoms were evaluated using the Insomnia Severity Index and the Hospital Anxiety and Depression Scale at baseline, post-treatment and 3-month follow-up. Repeated measures analysis of variance was used to assess the effectiveness of CBTi in treating insomnia, depressive symptoms and anxiety symptoms. A multivariate Cox regression model was used to determine the impact of depressive and anxiety symptoms on insomnia. Results: The study found significant reductions in insomnia, depressive symptoms and anxiety symptoms at both post-treatment and 3-month follow-up (F=17.45, p<0.001; F=36.37, p=0.001; and F=81.51, p<0.001, respectively). The duration of CBTi treatment had a positive impact on insomnia recovery (hazard ratio (HR)=0.94, p=0.018). However, baseline depressive symptoms (HR=1.83, p=0.004) and baseline anxiety symptoms (HR=1.99, p=0.001) had significant negative effects on insomnia recovery. Conclusions: The study showed that a 1-week self-guided CBTi treatment is effective in treating acute insomnia and comorbid depressive and anxiety symptoms. However, baseline depressive and anxiety symptoms negatively impact treatment effectiveness. Therefore, clinicians should assess for depressive and anxiety symptoms before treating acute insomnia with monotherapy CBTi.

Indexed as

anxietycognitive behavioral therapyCOVID-19depressionrisk factors

Identifiers

PMID37265474
PMCPMC10230965
OpenAlexW4377289123

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.