ArticleJournal of the American Chemical Society2023
Metallacarborane Cluster Anions of the Cobalt Bisdicarbollide-Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides.
Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- [60]Fullerene-Cluster Hybrids as Boron-Dense Delivery Nanoplatforms.Small science · 2026Article
- Antifungal metallacarboranes modulate Hsp90 activity.Future medicinal chemistry · 2026Article
- Artificial Transmembrane Channels for Selective Ascorbic Acid Transport and Bioorthogonal Signal Transduction.Angewandte Chemie (International ed. in English) · 2026Article
- Specific Ion Effects of Chaotropic and Superchaotropic Anions Probed by Raman Hydration-Shell Spectroscopy.Angewandte Chemie (International ed. in English) · 2026Article
- Functionalizing Injectable Hydrogels with Cobalt-Based Metallacarboranes for Targeted Delivery in Triple-Negative Breast Cancer.Chembiochem : a European journal of chemical biology · 2025Article
- Vertex Engineering of the Dodecaborate-Based Broadband Membrane Carriers.Inorganic chemistry · 2025Article
- Anionic Boron-Cluster BODIPY Conjugates As Promising Photosensitizers for Targeted Antimicrobial Photodynamic Therapy.ACS omega · 2025Article
- Metallacarboranes: abiotic scaffolds for advanced drug discovery.Future medicinal chemistry · 2025Article
- Analytical ultracentrifugation as a tool for exploring COSAN assemblies.European biophysics journal : EBJ · 2025Article
- Article
- Boron Clusters Escort Doxorubicin Squashing Into Exosomes and Overcome Drug Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Boron Cluster Anions Dissolve En Masse in Lipids Causing Membrane Expansion and Thinning.Angewandte Chemie (International ed. in English) · 2024Article
- Enhancing Membrane Permeability of Fluorescein-Type Chromophore Through Covalent Attachment of Chlorinated Dodecaborate.Molecules (Basel, Switzerland) · 2024Article
- A small-molecule carrier for the intracellular delivery of a membrane-impermeable protein with retained bioactivity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Carbon-Substituted Amines of the Cobalt Bis(dicarbollide) Ion: Stereochemistry and Acid-Base Properties.Inorganic chemistry · 2024Article
- All-Inorganic Polyoxometalates Act as Superchaotropic Membrane Carriers.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Chemistry of Carbon-Substituted Derivatives of Cobalt Bis(dicarbollide)(1Molecules (Basel, Switzerland) · 2023Review
- Boron Clusters Alter the Membrane Permeability of Dicationic Fluorescent DNA-Staining Dyes.ACS omega · 2023Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cobalt bisdicarbollides (COSANs) are inorganic boron-based anions that have been previously reported to permeate by themselves through lipid bilayer membranes, a propensity that is related to their superchaotropic character. We now introduce their use as selective and efficient molecular carriers of otherwise impermeable hydrophilic oligopeptides through both artificial and cellular membranes, without causing membrane lysis or poration at low micromolar carrier concentrations. COSANs transport not only arginine-rich but also lysine-rich peptides, whereas low-molecular-weight analytes such as amino acids as well as neutral and anionic cargos (phalloidin and BSA) are not transported. In addition to the unsubstituted isomers (known as
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.