Evidence map›Paper›PMID 37265330›Full record

ArticleOrganic & biomolecular chemistry2023

Anion-accelerated asymmetric Nazarov cyclization: access to vicinal all-carbon quaternary stereocenters.

Cody F Dickinson, Glenn P A Yap, Marcus A Tius

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cody F DickinsonDepartment of Chemistry, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA. tius@hawaii.edu.ORCID http://orcid.org/0000-0003-1318-4438
Glenn P A YapDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.ORCID http://orcid.org/0000-0003-0385-387X
Marcus A TiusDepartment of Chemistry, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA. tius@hawaii.edu.ORCID http://orcid.org/0000-0002-7092-8993

Funding

Synthesis and Optimization of the Aleutianamine Class of AlkaloidsR01GM145845 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HAMANN, MARK T, TIUS, MARCUS ANTONIUS · 2022 to 2025
$2.4M
Macromolecular X-ray Crystallographic Data Collection SystemS10OD026896 · OD · UNIVERSITY OF DELAWARE · PI BAHNSON, BRIAN J · 2020 to 2020
$580k
NIGMS NIH HHS R01 GM145845NIH HHS S10 OD026896
6 · The paper itself

Abstract

We have developed a catalytic asymmetric Nazarov cyclization that results in the formation of two contiguous all-carbon quaternary stereocenters in high yield with excellent levels of asymmetric induction. This method requires no catalyst recognition elements in the starting materials that are simple diketoesters. Geometrically pure

Identifiers

PMID37265330
PMCPMC10372926

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.