Evidence map›Paper›PMID 37264973›Full record

ArticleInternational journal of molecular medicine2023

Involvement of the JNK/HO‑1/FTH1 signaling pathway in nanoplastic‑induced inflammation and ferroptosis of BV2 microglia cells.

Jiayin Sun, Yihua Wang, Yilun Du, Wanxin Zhang, Zuodong Liu, Jin Bai, Guanqun Cui, Zhongjun Du

Open access · hybridAbstract read
In one paragraph

Article in International journal of molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
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  5. Liver Damage inBiology · 2026
    Article
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  11. The role of JNK signaling pathway in organ fibrosis.Journal of advanced research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jiayin SunDepartment of Toxicology, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Yihua WangDepartment of Applied Chemistry, Chemical Institute of Chemical Industry, Xinjiang University of Science and Technology, Korla, Xinjiang 841000, P.R. China.
Yilun DuArticular Surgery, Affiliated Hospital of Qinghai University, Xining, Qinghai 810000, P.R. China.
Wanxin ZhangDepartment of Toxicology, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Zuodong LiuDepartment of Toxicology, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Jin BaiDepartment of Toxicology, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Guanqun CuiDepartment of Respiratory Medicine, Children's Hospital Affiliated to Shandong University, Jinan, Shandong 250022, P.R. China.
Zhongjun DuDepartment of Toxicology, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong 250062, P.R. China.
Shandong First Medical University · CNQinghai University Affiliated Hospital · CNShandong University · CNXinjiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoplastics (NPs) are a newly discovered type of environmental pollutant. The potential for neurotoxicity caused by NPs and their mechanisms are unclear. The present study aimed to determine the molecular mechanism underlying neurotoxicity induced by NPs. Microglia (BV2) cells were used for

Indexed as

FerroptosisFerritinsHumansInflammationMAP Kinase Signaling SystemMicrogliaMicroplasticsOxidoreductasesReactive Oxygen SpeciesFerritinsFTH1 protein, humanMicroplasticsOxidoreductasesReactive Oxygen Speciesferroptosisinflammationmechanismmicrogliananoplastic

Identifiers

PMID37264973
PMCPMC10249580
OpenAlexW4379015018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.