ArticleClinical trials (London, England)2023
Now is the time to fix the clinical research workforce crisis.
Article in Clinical trials (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed.
- Implementation of a neuromuscular clinical trial network: a rare disease model for enhancing clinical trial readiness, capacity, and access in Canada.Orphanet journal of rare diseases · 2026Article
- An updated review of the SMA clinical trial landscape in the United States: Findings from analysis of recruitment targets on ClinicalTrials.gov and a survey of SMA clinical trial sites on factors affecting site capacity and readiness.Contemporary clinical trials communications · 2026Article
- Developing the future clinical research workforce: An immersive high school clinical research summer camp.Journal of clinical and translational science · 2026Article
- Evolving roles of Data Coordinating Centers in multisite research: Challenges and adaptations from a rapid scoping review.Journal of clinical and translational science · 2026Review
- Harmonizing interactions between clinical trial sponsors and study research sites: An appraisal of the key challenges and recommendations for addressing them.Journal of clinical and translational science · 2026Review
- Wellbeing for staff in UKCRC-registered Clinical Trials Units: Development of the Flourishing As Clinical Trial Staff (FACTS) guidance: a mixed-methods study.Contemporary clinical trials communications · 2025Article
- Building Pathways to Clinical Research Careers: Partnerships With Academic Programs to Provide Students With Experiential Learning Opportunities in Clinical Research.Academic medicine : journal of the Association of American Medical Colleges · 2025Article
- Understanding medical students' intercalation decisions to preserve the clinical academic pipeline: a mixed-method survey.BMC medical education · 2025Article
- The Erosion of Healthcare and Scientific Integrity: A Growing Concern.Journal of healthcare leadership · 2025Review
- Approaches and tools to measure individual-level research experience, activities, and outcomes: A narrative review.Journal of clinical and translational science · 2025Review
- Development of a job satisfaction measure for clinical research professionals: A mixed methods approach.Journal of clinical and translational science · 2025Article
- Completion of a standardizable competency-based research training program improves understanding and preparedness for both new and experienced clinical research professionals.Journal of clinical and translational science · 2025Article
- Real-world mastery of essential skills in a clinical research coordinator graduate program.Journal of clinical and translational science · 2025Article
- Trends in turnover and turbulence at a large academic medical center before and during COVID-19: Analyzing structured clinical research professional roles.Journal of clinical and translational science · 2025Article
- Assessment of competencies of clinical research professionals and proposals to improve clinical research in Portugal.Frontiers in pharmacology · 2025Article
- Greater gulf coast regional translational workforce development: Assessment and action plan.Journal of clinical and translational science · 2025Article
- An interprofessional model for training the next generation of physician-researchers.Journal of clinical and translational science · 2025Article
- Flourishing and job satisfaction in employees working in UK clinical trial units: a national cross-sectional survey.BMC health services research · 2024Article
- National Institute of Neurological Disorders and Stroke Clinical Trials Methodology Course: Summary and Accomplishments 2014-2023.Neurology. Education · 2024Review
- A Pilot Study on the Collection of Adverse Event Data from the Patient Using an Electronic Platform in a Cancer Clinical Trial Unit.Drugs - real world outcomes · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The clinical and translational research enterprise is recognized by many as the "evidence generation system." While there have been several calls to revolutionize this enterprise to more effectively deliver the fruits of biomedical science to patients and society, significant issues across the clinical research workforce are pervasive. Perhaps the most visible sign is the widening gap between supply and demand for competent staff. Underpinning this, is a perfect storm of complex issues. Now reaching crisis point, this problem is far bigger than a staffing issue and ultimately jeopardizes the "engine" of drug and device development. With the current perilous state of the workforce, proposed enterprise fixes are likely to languish far out of reach, given that even "business as usual" is under threat. In fact, a glaring disconnect is evident between the visionary discourse on how to revolutionize the clinical research enterprise and the sober recognition that operationalization of any such vision rests on the shoulders of a workforce that's in dire straits. In this article, we provide a brief forensic analysis of the workforce problem and an initial indication of where solutions may lie.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.