Evidence map›Paper›PMID 37264822›Full record

ArticleCancer discovery2023

Bridging the Gap between Diseases of the Stomach and Lower Esophagus.

Matthew D Stachler

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Cancer discovery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Highlights of how single-cell analyses are illuminating differentiation and disease in the gastric corpus.American journal of physiology. Gastrointestinal and liver physiology · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Matthew D StachlerDepartment of Pathology, University of California San Francisco, San Francisco, California.ORCID 0000-0003-0958-0286
University of California, San Francisco · US

Funding

Optimization and validation of a biomarker panel for risk stratification in Barrett's esophagusR37CA269649 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Matthew D Stachler · 2023 to 2026
$2.6M
NCI NIH HHS R37 CA269649
6 · The paper itself

Abstract

summaryIn this issue of Cancer Discovery, Nowicki-Osuch and colleagues perform an extensive characterization and analysis of single-cell RNA-sequencing data of the tubal gastrointestinal system, including a spectrum of inflammatory conditions and intestinal metaplasia of the stomach and esophagus. They show that both gastric and esophageal intestinal metaplasia share similarities at the transcript and protein levels. Interestingly, they show that individual cells within areas of metaplasia can coexpress transcriptional programs of both gastric and intestinal epithelia. See related article by Nowicki-Osuch et al., 1346 (6).

Indexed as

Precancerous ConditionsStomachEsophagusHumansMetaplasiaSequence Analysis, RNA

Identifiers

PMID37264822
OpenAlexW4379094693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.