Evidence map›Paper›PMID 37264707›Full record

ArticleJournal of veterinary internal medicine

Effect of diet composition on glandular gastric disease in horses.

Samy Julliand, Marjorie Buttet, Tanguy Hermange, Patrick Hillon, Véronique Julliand

Open access · goldAbstract readObservational Study, VeterinaryMulticenter Study
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Samy JulliandUMR PAM A 02.102, Dijon, France.ORCID https://orcid.org/0000-0002-3670-374X
Marjorie ButtetLab To Field, Dijon, France.
Tanguy HermangeCentre Hospitalier Vétérinaire Equin de Livet, Livarot-Pays-d'Auge, France.
Patrick HillonUniversity of Bourgogne-Franche Comté, Dijon, France.
Véronique JulliandUMR PAM A 02.102, Dijon, France.
Fielding Graduate University · USInserm · FRLiv Hospital · TRProcédés Alimentaires et Microbiologiques · FRUniversité de Bourgogne · FR

Funding

CASDAR (French Ministry of Agriculture and Food)
6 · The paper itself

Abstract

backgroundNutritional factors are suggested to influence the incidence and severity of glandular gastric disease (GGD) in horses.

objectivesTo retrospectively assess whether dietary fermentable carbohydrates increase the severity of GGD and to prospectively evaluate whether the partial substitution of concentrates by dehydrated alfalfa would decrease GGD severity scores. ANIMALS: In total, 82 trotters from 4 training centers exercised ≥5 days/week.

methodsMulticenter retrospective observational study, and prospective 2-arm randomized trial. Glandular mucosae were observed by gastroscopy and scored (0-4 severity scale) at day 0 (D0). Biochemical composition of the diet fed was compared between ulcerated and nonulcerated groups. After D0, horses either received the same diet (control, n = 41) or pelleted dehydrated alfalfa substituting 50% concentrates (alfalfa, n = 41). Glandular scores were recorded in both groups after 21 (D21) and 42 days (D42). The first end point was a successful outcome, defined as a horse with a glandular score of 2 to 4 on D0, decreasing to a score of 0 to 1 on days 21 or 42.

resultsHorses scored 0 to 1 at D0 ingested more (P = .01) soluble sugars from concentrates than those scored 2 to 4 before D0 (77.5 g/kg BW; 95% confidence interval [CI]: 71.1-84.0, vs 59.1 g/kg BW; 95% CI: 48.0-70.3), whereas starch intake did not differ between groups (P = .24). Among horses scored 2 to 4 at D0, fewer were scored 2 to 4 in the alfalfa group (1 out of 6) compared with the control group (6 out of 6) at D42 (P = .02). Clinical success was 47.7 times more likely in horses fed alfalfa compared with horses in the control group (95% CI: 1.6-1422.8). CONCLUSION AND CLINICAL IMPORTANCE: Relationships were found between diet composition and integrity of the glandular mucosa. Feeding pelleted dehydrated alfalfa could help to reduce the incidence and severity of GGD.

Indexed as

Horse DiseasesStomach DiseasesStomach UlcerAnimal FeedAnimalsDietGastroscopyHorsesProspective StudiesRetrospective Studiesbuffering capacityFrench trottersgastric ulcerpelleted alfalfasimple sugars

Identifiers

PMID37264707
PMCPMC10365063
OpenAlexW4379094895

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.