Evidence map›Paper›PMID 37264402›Full record

ReviewMolecular cancer2023

The role of m6A methylation in therapy resistance in cancer.

Hengzhao Zhuang, Bo Yu, Dan Tao, Xiaoyan Xu, Yijun Xu, Jian Wang, Yang Jiao, Lili Wang

Open access · goldAbstract readReview
In one paragraph

Review in Molecular cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed
29.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 187 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Reprogramming resistance in advanced lung cancer: epigenetic modulation to restore therapeutic vulnerability.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  5. Article
  6. METTL3-YTHDF1-driven mMolecular and cellular biochemistry · 2026
    Article
  7. PRRC2A-mediated mCell death & disease · 2026
    Article
  8. Article
  9. The relevance of mJournal of cancer research and clinical oncology · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Emerging roles of RNA mInternational journal of oncology · 2026
    Review
  17. Article
  18. Targeting mDiscover oncology · 2026
    Review
  19. Article
  20. Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hengzhao Zhuang *Department of Radiation Oncology, The First Affiliated Hospital of Soochow University, Suzhou, 21500, China.
Bo Yu *Department of Radiotherapy, The Affiliated Jiangyin People's Hospital of Nantong University, Jiangyin, 214400, China.
Dan Tao *Department of Radiation Oncology, Dushu Lake Hospital Affiliated to Soochow University, Suzhou, 21500, China.
Xiaoyan XuDepartment of Radiation Oncology, The First Affiliated Hospital of Soochow University, Suzhou, 21500, China.
Yijun XuDepartment of Radiation Oncology, The First Affiliated Hospital of Soochow University, Suzhou, 21500, China.
Jian WangDepartment of Radiotherapy, The Affiliated Jiangyin People's Hospital of Nantong University, Jiangyin, 214400, China. 1627879372@qq.com.
Yang JiaoSchool of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou, 215000, China. jiaoyang@suda.edu.cn.
Lili WangDepartment of Radiation Oncology, The First Affiliated Hospital of Soochow University, Suzhou, 21500, China. wanglili@suda.edu.cn.
First Affiliated Hospital of Soochow University · CNSoochow University · CNJiangyin People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer therapy resistance is the main cause of cancer treatment failure. The mechanism of therapy resistance is a hot topic in epigenetics. As one of the most common RNA modifications, N6-methyladenosine (m6A) is involved in various processes of RNA metabolism, such as stability, splicing, transcription, translation, and degradation. A large number of studies have shown that m6A RNA methylation regulates the proliferation and invasion of cancer cells, but the role of m6A in cancer therapy resistance is unclear. In this review, we summarized the research progress related to the role of m6A in regulating therapy resistance in cancers.

Indexed as

NeoplasmsEpigenesis, GeneticHumansMethylationRNARNA SplicingRNACancerChemoresistancem6A methylationRadiotherapy resistance

Identifiers

PMID37264402
PMCPMC10233906
OpenAlexW4378981901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.