Evidence map›Paper›PMID 37264368›Full record

ArticleFluids and barriers of the CNS2023

The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis.

Ivana Lazarevic, Sasha Soldati, Josephine A Mapunda, Henriette Rudolph, Maria Rosito, Alex Cardoso de Oliveira, Gaby Enzmann, Hideaki Nishihara, Hiroshi Ishikawa, Tobias Tenenbaum and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Fluids and barriers of the CNS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 57 citations in OpenAlex.

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  11. Gut-brain axis in health and brain disease.Chinese medical journal · 2026
    Review
  12. The spleen-brain axis in Alzheimer's disease and related dementias: Integrating immune and metabolic regulation.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Ivana Lazarevic *Theodor Kocher Institute, University of Bern, Freiestrasse 1, Bern, CH-3012, Switzerland.
Sasha Soldati *Theodor Kocher Institute, University of Bern, Freiestrasse 1, Bern, CH-3012, Switzerland.
Josephine A Mapunda *Theodor Kocher Institute, University of Bern, Freiestrasse 1, Bern, CH-3012, Switzerland.
Henriette RudolphKlinik für Kinder - und Jugendmedizin, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Maria RositoTheodor Kocher Institute, University of Bern, Freiestrasse 1, Bern, CH-3012, Switzerland.
Alex Cardoso de OliveiraTheodor Kocher Institute, University of Bern, Freiestrasse 1, Bern, CH-3012, Switzerland.
Gaby EnzmannTheodor Kocher Institute, University of Bern, Freiestrasse 1, Bern, CH-3012, Switzerland.
Hideaki NishiharaTheodor Kocher Institute, University of Bern, Freiestrasse 1, Bern, CH-3012, Switzerland.
Hiroshi IshikawaLaboratory of Clinical Regenerative Medicine, Department of Neurosurgery, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan.
Tobias TenenbaumKlinik für Kinder - und Jugendmedizin, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Horst SchrotenKlinik für Kinder - und Jugendmedizin, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Britta EngelhardtTheodor Kocher Institute, University of Bern, Freiestrasse 1, Bern, CH-3012, Switzerland. britta.engelhardt@tki.unibe.ch.
University of Bern · CHHeidelberg University · DESapienza University of Rome · ITUniversity Hospital Heidelberg · DEUniversity of Tsukuba · JPYamaguchi University · JP

Funding

JSPS 22K15711JSPS under the Joint Research Program implemented in association with SNSF (JRPs) JPJSJRP20221507Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PDFMP3_137127Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung,Switzerland PDAMP3_137087
6 · The paper itself

Abstract

The choroid plexus (ChP) has been suggested as an alternative central nervous system (CNS) entry site for CCR6

Indexed as

Encephalomyelitis, Autoimmune, ExperimentalAnimalsBrainCentral Nervous SystemChoroid PlexusMiceMice, Inbred C57BLNeuroinflammatory DiseasesCCL20Choroid plexusExperimental autoimmune encephalomyelitisT cell traffickingTh17 cells

Identifiers

PMID37264368
PMCPMC10236715
OpenAlexW4378980314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.