Evidence map›Paper›PMID 37264220›Full record

ArticleNeuroradiology2023

Comparison of quantitative FDG-PET and MRI in anti-LGI1 autoimmune encephalitis.

Mohammad S Sadaghiani, Samantha Roman, Luisa A Diaz-Arias, Ralph Habis, Arun Venkatesan, John C Probasco, Lilja B Solnes

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Persistent Bilateral [Annals of clinical and translational neurology · 2026
    Article
  4. Journal of neurology · 2026
    Article
  5. Article
  6. MedComm · 2025
    Article
  7. Article
  8. Article
  9. Quantitative brainAnnals of clinical and translational neurology · 2024
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mohammad S SadaghianiDivision of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N. Caroline St., Baltimore, MD, 21287, USA.
Samantha RomanDepartment of Neurology, Johns Hopkins University School of Medicine, 601 N. Caroline St., Baltimore, MD, 21287, USA.
Luisa A Diaz-AriasDepartment of Neurology, Johns Hopkins University School of Medicine, 601 N. Caroline St., Baltimore, MD, 21287, USA.
Ralph HabisDepartment of Neurology, Johns Hopkins University School of Medicine, 601 N. Caroline St., Baltimore, MD, 21287, USA.
Arun VenkatesanDepartment of Neurology, Johns Hopkins University School of Medicine, 601 N. Caroline St., Baltimore, MD, 21287, USA.
John C Probasco *Department of Neurology, Johns Hopkins University School of Medicine, 601 N. Caroline St., Baltimore, MD, 21287, USA. jprobas1@jhmi.edu.ORCID http://orcid.org/0000-0003-2095-0786
Lilja B Solnes *Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N. Caroline St., Baltimore, MD, 21287, USA. lsolnes1@jhmi.edu.
Johns Hopkins University · US

Funding

Training for Clinician Scientists in Imaging ResearchT32EB006351 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI POMPER, MARTIN G · 2006 to 2022
$4.0M
NIBIB NIH HHS T32 EB006351NIBIB NIH HHS T32EB006351
6 · The paper itself

Abstract

objectivesAnti-leucine glioma-inactivated protein 1 (anti-LGI1) autoimmune encephalitis (AE) presents as subacute memory loss, behavioral changes, and seizures. Diagnosis and treatment delays can result in long term sequelae, including cognitive impairment.

methodsNineteen

resultsAll

conclusionsBrain FDG uptake was more commonly abnormal than MRI in the pre-treatment phase of anti-LGI1, and patterns of dysmetabolism differed in the pre-treatment and convalescent phases. These findings may expedite the diagnosis, treatment, and monitoring of anti-LGI1 patients.

Indexed as

Autoimmune Diseases of the Nervous SystemGliomaConvalescenceEncephalitisFluorodeoxyglucose F18Hashimoto DiseaseHumansLeucineMagnetic Resonance ImagingPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18LeucineAnti-LGI1Autoimmune encephalitisFDG PET/CT

Identifiers

PMID37264220
PMCPMC10338588
OpenAlexW4379094109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.