Evidence map›Paper›PMID 37264166›Full record

ArticleAging clinical and experimental research2023

Differential associations of clinical features with cerebrospinal fluid biomarkers in dementia with Lewy bodies and Alzheimer's disease.

Fabricio Ferreira de Oliveira, Marjorie Câmara Miraldo, Eduardo Ferreira de Castro-Neto, Sandro Soares de Almeida, Sandro Luiz de Andrade Matas, Paulo Henrique Ferreira Bertolucci, Maria da Graça Naffah-Mazzacoratti

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In one paragraph

Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Lewy Body Dementia Research in Latin America: A Scoping Review.Movement disorders clinical practice · 2025
    Article
  5. Article
  6. Behavioral disorders in dementia with Lewy bodies: old and new knowledge.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fabricio Ferreira de OliveiraDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Federal University of São Paulo (UNIFESP), Rua Botucatu 740, Vila Clementino, São Paulo, SP, 04023-900, Brazil. fabricioferreiradeoliveira@hotmail.com.ORCID http://orcid.org/0000-0002-8311-0859
Marjorie Câmara MiraldoDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Federal University of São Paulo (UNIFESP), Rua Botucatu 740, Vila Clementino, São Paulo, SP, 04023-900, Brazil.ORCID http://orcid.org/0000-0002-1035-027X
Eduardo Ferreira de Castro-NetoDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Federal University of São Paulo (UNIFESP), Rua Botucatu 740, Vila Clementino, São Paulo, SP, 04023-900, Brazil.ORCID http://orcid.org/0000-0002-2073-3004
Sandro Soares de AlmeidaDepartment of Biophysics, Escola Paulista de Medicina, Federal University of São Paulo (UNIFESP), São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-4392-0953
Sandro Luiz de Andrade MatasDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Federal University of São Paulo (UNIFESP), Rua Botucatu 740, Vila Clementino, São Paulo, SP, 04023-900, Brazil.ORCID http://orcid.org/0000-0002-0479-2450
Paulo Henrique Ferreira BertolucciDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Federal University of São Paulo (UNIFESP), Rua Botucatu 740, Vila Clementino, São Paulo, SP, 04023-900, Brazil.ORCID http://orcid.org/0000-0001-7902-7502
Maria da Graça Naffah-MazzacorattiDepartment of Neurology and Neurosurgery, Escola Paulista de Medicina, Federal University of São Paulo (UNIFESP), Rua Botucatu 740, Vila Clementino, São Paulo, SP, 04023-900, Brazil.ORCID http://orcid.org/0000-0002-3468-360X
Universidade Federal de São Paulo · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/10109-5Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/18125-0
6 · The paper itself

Abstract

aimTo explore associations of cerebrospinal fluid biomarkers of neurodegeneration and amyloidosis with caregiver burden, cognition and functionality in dementia with Lewy bodies (DLB) paired with late-onset Alzheimer's disease (AD) and healthy older people.

methodsConsecutive outpatients with DLB were matched with outpatients with AD according to sex, cognitive scores and dementia stage, and with cognitively healthy controls according to age and sex to investigate associations of cerebrospinal fluid amyloid-β (Aβ

resultsOverall, 27 patients with DLB (78.98 ± 9.0 years-old; eleven APOE-ε4 +) were paired with 27 patients with AD (81.50 ± 5.8 years-old; twelve APOE-ε4 +) and 27 controls (78.98 ± 8.7 years-old; four APOE-ε4 +); two-thirds were women. In AD, Aβ

conclusionsCerebrospinal fluid phospho-tau Thr

Indexed as

Alzheimer DiseaseLewy Body DiseaseAgedAged, 80 and overalpha-SynucleinAmyloid beta-PeptidesApolipoproteins EBiomarkersFemaleHumansMalePeptide Fragmentstau Proteinsalpha-SynucleinAmyloid beta-PeptidesApolipoproteins EBiomarkersPeptide Fragmentstau ProteinsActivities of daily livingAlzheimer’s diseaseApoECerebrospinal fluidCognitive disordersLewy body dementia

Identifiers

PMID37264166
OpenAlexW4379094536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.