ArticleScientific reports2023
The risk of colorectal cancer according to obesity status at four-year intervals: a nationwide population-based cohort study.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review: The gut microbiota as a link between colorectal cancer and obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Pooled it
- Influence of BMI on robotic rectal cancer surgery: a systematic review and meta-analysis.Journal of robotic surgery · 2025Pooled it
- Body Roundness Index and Incident Colorectal Cancer Risk: A Nationwide Population-Based Cohort Study.Cancers · 2026Article
- Fatty Acid Metabolism and Hypoxia in the Tumor Microenvironment: Metabolic Adaptation and Clinical Potential in Colorectal Cancer.Biomedicines · 2026Review
- Article
- A prospective investigation of early-onset colorectal cancer risk factors-pooled analysis of three large-scale European cohorts.British journal of cancer · 2026Article
- Nationwide Big Data Studies of Endocrine Diseases Using the Korean National Health Information Database: Research Trends and Standardization of Operational Definitions.Endocrinology and metabolism (Seoul, Korea) · 2026Review
- Obesity and colorectal cancer risk: A systematic review and meta-analysis.World journal of clinical oncology · 2026Article
- Obesity Promotes Renal Inflammation and Fibrosis Independent of Sex in SS Leptin Receptor Mutant (SSBiomedicines · 2025Article
- Mendelian randomisation analysis to discover plasma metabolites mediating the effect of obesity on cancer risk.British journal of cancer · 2025Article
- Murine Models of Obesity-Related Cancer Risk.Cancer prevention research (Philadelphia, Pa.) · 2025Review
- Outcomes of robotic, laparoscopic, and open surgery across body mass index subgroups for colon and rectal cancer.Surgical endoscopy · 2025Article
- Expression of VISTA on T cells in patients with cancer colon.Journal of the Egyptian National Cancer Institute · 2025Article
- System genetic analysis of intestinal cancer and periodontitis development as influenced by aging and diabesity using Collaborative Cross mice.Animal models and experimental medicine · 2025Review
- The role of adipogenic niche resident cells in colorectal cancer progression in relation to obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Review
- Special Diets and Nutrient Intakes in Morbidly Obese US Adults in Comparison to the 2020-2025 Dietary Guidelines for Americans.Nutrition journal · 2025Article
- Evaluation of the Antioxidant and Anti-Cancer Potential of Microwave-AssistedCurrent issues in molecular biology · 2025Article
- Development and interpretation of a machine learning model for predicting body mass index in Chinese adolescents: a prospective cohort study.Frontiers in public health · 2025Article
- Spatial analysis of risk factors related to colorectal cancer in Iran: An ecological study.Health science reports · 2024Article
- Obesity-Associated Colorectal Cancer.International journal of molecular sciences · 2024Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a risk factor for colorectal cancer. However, the effect of body weight change on colorectal cancer is uncertain. This study aimed to investigate the relationship between difference in body mass index and the risk of colorectal cancer. In this nationwide population-based cohort study, participants of the national cancer screening program in 2005 and 2009 were enrolled. Difference of body mass index was calculated from screening data from 2005 and 2009. Participants were divided into four groups according to direction of obesity status: non-obese/non-obese, non-obese/obese, obese/non-obese, and obese/obese. The effect of differences in body mass index on colorectal cancer was analyzed. Among 3,858,228 participants, 47,894 (1.24%) participants were newly diagnosed with colorectal cancer during the 9.2 years of follow-up. The incidence of colorectal cancer was higher in the obese/obese group than the non-obese/non-obese group (hazard ratio = 1.08 [1.06-1.11], P trend < 0.001). The men in the obese/obese group had a higher risk of colon cancer than women (hazard ratio = 1.13 [1.10-1.17] in men, and hazard ratio = 1.04 [1.01-1.18] in women, P = 0.001). Persistent obesity was associated with a higher risk of incidence of colorectal cancer.
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