Evidence map›Paper›PMID 37264061›Full record

Trial reportScientific reports2023

Part two: an unblinded, parallel, randomized study to assess nicotine pharmacokinetics of four Vuse Solo ENDS flavors in smokers.

Brian M Keyser, Kyung Soo Hong, Patricia DeLuca, Tao Jin, Bobbette A Jones, Paul Nelson, Eckhardt Schmidt, Elaine K Round

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Brian M KeyserRAI Services Company, 401 N. Main Street, Winston-Salem, NC, 27101, USA.
Kyung Soo HongRAI Services Company, 401 N. Main Street, Winston-Salem, NC, 27101, USA.
Patricia DeLucaRAI Services Company, 401 N. Main Street, Winston-Salem, NC, 27101, USA. delucap2@rjrt.com.
Tao JinRAI Services Company, 401 N. Main Street, Winston-Salem, NC, 27101, USA.
Bobbette A JonesRAI Services Company, 401 N. Main Street, Winston-Salem, NC, 27101, USA.
Paul NelsonRAI Services Company, 401 N. Main Street, Winston-Salem, NC, 27101, USA.
Eckhardt SchmidtRAI Services Company, 401 N. Main Street, Winston-Salem, NC, 27101, USA.
Elaine K RoundRAI Services Company, 401 N. Main Street, Winston-Salem, NC, 27101, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the findings from a randomized, parallel study designed to evaluate nicotine pharmacokinetics (PK) following 10 min of ad libitum use of electronic nicotine delivery system (ENDS) in four flavor variants. Subjects were randomized an investigational product (IP) and blood samples were collected for PK assessments during a test session. Primary endpoints were baseline-adjusted values of maximum plasma nicotine concentration (C

Indexed as

Electronic Nicotine Delivery SystemsTobacco ProductsHumansNicotineSmokersNicotine

Identifiers

PMID37264061
PMCPMC10235118

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.